Anyone on or have taken Motegrity?

Yes, Motegrity has helped me but I had to play around with the dosage. I started with a 1/4 of a 2mg tablet then went up to 1/2 a tablet at bedtime. It seems to work with less side effects at lower a dose.

Is it ok to cut them? The issue I will soon be running into is that I will be going on Medicare at the end of the year. Since it is relatively new, it is not on the formulary and will cost me a fortune, so I’m trying to find cheaper things that will work as well.

I tried Motegrity 2 times…both times I got such a weird BAD headache…it felt like the back of my head was gonna explode…needless to say, I never took it again. At that time,it was still in trial, I called & reported my issue.

I’m also new to Motegrity. I also take Amitiza- fairly new to that too.
I’m still experimenting with how often I take it.
I take Amitiza twice a day- except when I have a relapse of what I assume is my autoimmune colitis.
Motegrity work most of the time, but I ration it.
I’m also on Medicare- $200 a month. On Medicare one doesn’t qualify for the manufacturer’s discount coupons.

Yes, you can cut Motegrity.
I have Medicare and with a Prior Auth got it approved, but I did have to try several others first.

I tried Motegrity. It made me so sick I stopped it.
The mixture of applesauce, oat bran and prune juice along with a small amount of saline version of Milk of Mag has worked so much better.
I am still trying to get into a Clinical trials endoscopy procedure for my Gastroparesis.
I just stay on my diet until I can something better done!

I started taking Motegrity, stopped laxatives and the results were great for about 6 months!!! I’m back to taking a laxative every 3rd day!!! Not happy! Will soon see my doctor!!!

I take Motegrity for my SIBO, I am also constipated.
It is my understanding that you need to give it a two week break every 3 months ( your body gets use to it)
Have you tried Magnesium citrate or glycinate?

Magnesium Citrate helps me…MoM gives me MAJOR gas

I take Vitacost's 400 mg magnesium citrate at night with calcium, and vit D for my bones. It helps with my obstipation. How to balance the constipating effect of supplemental calcium with its also being necessary for bone strength is challenging.
My GI rx Motegrity, but I find occasional Miralax and a stool softener plus enjoying plenty of fall fruit is working for the moment.
Can you say more about the quarterly 2 week break from Motegrity?