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MGUS with Polycythemia Vera (PV)
Blood Cancers & Disorders | Last Active: May 6, 2023 | Replies (38)Comment receiving replies
Finally received the results of my BMB. Polycythemia Vera was confirmed. Additionally, my MGUS has progressed. My plasma cells have increased to 10-15% & my kappa/lambda light chain ratio is 0.05. M-spike is 2.5. I interpret this as intermediate risk smoldering myeloma. I have an appointment with my hematologist this Wednesday to discuss.
My biggest question is how common is it to have PV & MGUS (or SMM) at the same time? I assume it is better to focus on the PV and did have a phlebotomy a week ago (1 unit of blood) before the BMB. Blood tests are scheduled during my upcoming appointment. Thanks for your response.
Replies to "Finally received the results of my BMB. Polycythemia Vera was confirmed. Additionally, my MGUS has progressed...."
I have had MGUS, then smouldering myeloma since 2013 with very small increases. 2 years ago I found out I now have polycythemia vera. I am watch and wait on the myeloma but have labs often and take Hydroxyurea for the pv. Pv is an amyloid problem and myeloma is a myeloid problem, both in bone marrow but unrelated. Aren't we special?
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Don't know the answers to any of your questions. I have SMM too, with an M spike of 5, and but don't have the results of my cuurent labs yet. My major problem is iron deficiency anemia. I was on Methotrexate for a few years for RA and quit. It was making my anemia worse, Had to have a lot of blood transfusions. I hope that you have a really good hematologist. On FB, if you are on it there is a great group for SMM.