1. < Neuropathy

Has anyone tried anti-depressant medication for neuropathic pain?

Posted by greenacres @greenacres, Nov 13, 2021

I'm wondering how many people in this community with neuropathic pain have been prescribed some form of an anti-depressant along with or without Gabapentin to help ease the pain and if anyone has found this protocol helpful?

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virginiashort | @virginiashort | Apr 14, 2022

I’m taking Duloxetine with Gabapenten….and I think it eases the burning in my lower legs. I have small fiber neuropathy

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vicjfaoro1 | @vicjfaoro1 | Apr 14, 2022
In reply to @tgregg99 "I took 10mg nortriptyline for awhile for pain management (spinal issues), and in the process of..." + (show)
@tgregg99

I took 10mg nortriptyline for awhile for pain management (spinal issues), and in the process of taking it I found that taking it did provide some relief for my PN numbness (toes), and I slept well too. However, the minor sedation effect upon waking was not working out, so I tapered off the nortriptyline. I tried Gapapentin once after my PN diagnosis but it did not relieve my PN numbness so I stopped taking it. A 500 mg acetaminophen tab at bedtime does help me sleep, as does wearing warm thick socks. So far, I've found no lasting relief for my PN numbness but I'm scheduled to see a new neurologist soon for a discussion, so my search continues.

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Interesting info on gabepentin and sleep. My son is on 900mg and takes prior to bedtime. Can’t sleep so maybe your suggestion.

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vicjfaoro1 | @vicjfaoro1 | Apr 14, 2022

This is from a caretaker for a peripheral pilyneuropathy patient who takes citaloprin and lisinopril. He falls asleep at the drop of a hat after working 4-5 hours max

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willows | @willows | Apr 14, 2022

Pregabalin and amitriptyline works well for me. It’s

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vicjfaoro1 | @vicjfaoro1 | Apr 16, 2022
In reply to @rivermaya34 "I tried several of those way earlier before my diagnosis and my body didn't respond well..." + (show)
@rivermaya34

I tried several of those way earlier before my diagnosis and my body didn't respond well to them at all. I was recently prescribed one new one (I still take Gabapentin), but I have not taken it yet because I remember my Mom taking it a long time ago and having very adverse effects. BUT...I know that each individual responds differently to medication combinations, so I'd say all you can do is research it and maybe try, then make a decision on how to proceed. Hope that helps. Good luck to you

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I’m new to the group so not sure how I see what your post was responding to regarding meds with gabapentin. I’m Mom of a poly neuropathy patient. Thanks for your help

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loujentez3 | @loujentez3 | Apr 16, 2022
In reply to @willows "Amitriptyline and Lyrica work well for me to control pain. Both agree with me and the..." + (show)
@willows

Amitriptyline and Lyrica work well for me to control pain. Both agree with me and the only side effect is occasional dry mouth. I hope you can find the right combination for you.

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Thank you so much for information I will mention it to my Dr. On my upcoming visit

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1 reply
loujentez3 | @loujentez3 | Apr 16, 2022
In reply to @loujentez3 "Thank you so much for information I will mention it to my Dr. On my upcoming..." + (show)
@loujentez3

Thank you so much for information I will mention it to my Dr. On my upcoming visit

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Is there any treatment that the mayo clinic has to treat Sfn? I seem to be getting much worse looking for help and meds to help

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1 reply
trishh | @trishh | Apr 17, 2022
In reply to @loujentez3 "Is there any treatment that the mayo clinic has to treat Sfn? I seem to be..." + (show)
@loujentez3

Is there any treatment that the mayo clinic has to treat Sfn? I seem to be getting much worse looking for help and meds to help

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@lougentez3. I am wondering the same thing. Does Mayo have any recommendations for treatment of SFN. My neurologist said to try Cymbalta and use lidocaine cream I have for another condition. So exhausted from PAIN and allergic to Gabepentin.

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1 reply
virginiashort | @virginiashort | Apr 18, 2022
In reply to @trishh "@lougentez3. I am wondering the same thing. Does Mayo have any recommendations for treatment of SFN...." + (show)
@trishh

@lougentez3. I am wondering the same thing. Does Mayo have any recommendations for treatment of SFN. My neurologist said to try Cymbalta and use lidocaine cream I have for another condition. So exhausted from PAIN and allergic to Gabepentin.

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I am taking Gabapenten and Duloxetine and am doing ok

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2 replies
trishh | @trishh | Apr 18, 2022
In reply to @virginiashort "I am taking Gabapenten and Duloxetine and am doing ok" + (show)
@virginiashort

I am taking Gabapenten and Duloxetine and am doing ok

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Thanks you, I have any anaphylactic reaction to Gabepentin.

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