C. diff relapse?

Posted by patts @patts, Sep 1, 2019

How many have had a relapse. I finished my two weeks of vancomycin and believe I still have it. Did a stool sample Friday, so I guess I’ll see. Tired of isolation, Clorox and mood.

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Profile picture for virginiaj @virginiaj

My husband has had C.diff since late December. Is on 3rd round of Vanco and had one round of Dificid. The copay on Dificid was $1500. The first Vanco had a copay of $28, the second a copay of $450. When he got the 3rd prescription, his Part D drug plan said he couldn’t get a refill (even when prescribed by infectious medicine doc. Pharmacist suggested using goodRX, where we bought it for $300. His doctor sent a letter to drug plan and now they may cover it again but goodRX will be cheaper. He is now tapering slowly so hope it works. He is better, but not back to normal.

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Those are wild prices for the Vanco. I picked up my RX for use in tapering today from Kroger and was astonished that the cost for 14 day dosage was just $4.24! Last time I got it from Publix, it was $24 so crazy fluctuations in what you are having to pay! So sorry. Dificid seems to be the really pricey one. So hoped it would work but didn’t.

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Profile picture for virginiaj @virginiaj

My husband has had C.diff since late December. Is on 3rd round of Vanco and had one round of Dificid. The copay on Dificid was $1500. The first Vanco had a copay of $28, the second a copay of $450. When he got the 3rd prescription, his Part D drug plan said he couldn’t get a refill (even when prescribed by infectious medicine doc. Pharmacist suggested using goodRX, where we bought it for $300. His doctor sent a letter to drug plan and now they may cover it again but goodRX will be cheaper. He is now tapering slowly so hope it works. He is better, but not back to normal.

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What is the purpose behind tapering? I guess I don’t understand how that works when taking the full dosing didn’t get rid of it. Please elaborate. I’ve heard of tapering but wasn’t sure about how it’s supposed to help? Prayers that it works for your husband and all of us.

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Profile picture for cre8tive @cre8tive

What is the purpose behind tapering? I guess I don’t understand how that works when taking the full dosing didn’t get rid of it. Please elaborate. I’ve heard of tapering but wasn’t sure about how it’s supposed to help? Prayers that it works for your husband and all of us.

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He would be improving on the full dose, but not be back to normal. As soon as he was off the drug, the diarrhea got worse. I guess the tapering is to try to stop that pattern

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Profile picture for p95 @p95

Oh my goodness. Terrible. How did you get rid of the C. Diff? Flagyl, Vancomycin, Deficid? Any of these work for you?

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I just read here that Mayo Dr. told someone that she will always test positive for C-diff. Is this true? I just tested positive again on a stool sample after finishing Vanco a week later. From reading here, Dificid is the best to try so I just told my Dr. to prescribe it. My co-payment is $50 and the meds cost $7000 for 2 wk supply. That is so unheard of...

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Profile picture for cre8tive @cre8tive

I’m curious about the cost of your Dificid? Mine was “covered” by insurance but still cost me $1300 out of pocket versus $20 for Vanco. Have you been able to get Dificid at a reasonable cost? It’s actually supposed to work better than Vanco but neither have worked for me. Just curious?

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Just picked up my Dificid, at Walgreens. $7257.00!!!!!!!!!!!!! My co-pay was $50. thank goodness. Really hoping it works since Vanco did not. For this price, we should all be getting a new stomach makeover....Praying for no side effects...

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Profile picture for p95 @p95

Hi, I 'm new here. I have a question about whether my C. Diff. is gone or not. I have had IBS for 10 years and the symptoms are the same except my C. Diff stool has a sickening sweet smell still. I was diagnosed with C. Diff on 1-28-22 and my GI doc started me on Flagyl (metronidazole) for 14 days. After 11 days, the cramping had stopped, but I still had diarrhea with belly distension and smelly stool so I called my GI doc and he ordered Vancomycin 250 mg 4 times a day for 14 days. I started the Vanco on 2-11-22 and am now on the 10th day of that. I had a couple of days where my first stool of the day was formed but the 4 movements afterward were diarrhea. Today, I'm back to very loose stools all morning. So basically, I've been on antibiotics for 3 weeks and have morning diarrhea with that sickening sweet smell. Usually, with my IBS, the diarrhea would stop by noon and I was fine the rest of the day until the next morning, but my stool was not that sickening sweet smell. My IBS always vacillated between diarrhea and constipation so I'm wondering if I still have the C. Diff. since now, I'm done with the diarrhea by 11 am, but my diarrhea still has that sickening smell. Anybody else experienced anything like this?

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The only tapering off strategy that helped my husband was with cholestyramine. It is an off label prescription that his gastroenterologist used after every antibiotic failed.

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Profile picture for minge @minge

Currently 3 weeks recovery from C-Diff after taking vancomycin . I have two questions.
I am scheduled for a routine colonoscopy in November (5 years since last colonoscopy). That will only be 2 months of recovery time from C-Diff. Will the colonoscopy create a relapse of C-Diff? Should I wait to have the colonoscopy since this is a routine 5 year check?
Second question is I am due for a tetanus shot (10 years since last one) Can I get the tetanus shot or will it create a relapse of C-Diff?
I do not want a relapse of C-Diff and I am only 3 weeks into recovery!

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After my husband suffered from C-diff for six months, his gastroenterologist prescribed cholestyramine which is actually a cholesterol lowering drug. None of the antibiotics helped but cholestyramine stabilized his gut.

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Profile picture for lengel @lengel

After my husband suffered from C-diff for six months, his gastroenterologist prescribed cholestyramine which is actually a cholesterol lowering drug. None of the antibiotics helped but cholestyramine stabilized his gut.

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I am on the same drug for chronic diarrhea. It got so bad I felt I could not leave my house. I have never had c-diff and although I was diagnosed with Crohns 50+ years ago, I have been on no medicine and healthy. My problem was the diarrhea from having all but 9 inches of my colon removed 50 years ago. Cholestrymine keeps it to a manageable level. BTW it was an internist, not a gastro that prescribed it and saved me.

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Profile picture for sbr270 @sbr270

I am on the same drug for chronic diarrhea. It got so bad I felt I could not leave my house. I have never had c-diff and although I was diagnosed with Crohns 50+ years ago, I have been on no medicine and healthy. My problem was the diarrhea from having all but 9 inches of my colon removed 50 years ago. Cholestrymine keeps it to a manageable level. BTW it was an internist, not a gastro that prescribed it and saved me.

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So thankful that your internist was able to help!

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Profile picture for euqcaj @euqcaj

Hi This is Jacque again. I need some reassurance. I have now been put on Amoxicillian for dental pain, switching from Doxycyline. (It just wasn't getting rid of the jaw pain.) I have a deeply broken root. BUT my question is: In your reply above, you mentioned that Amoxicillian "is safe for c-diff sufferers." I pray this is true. I am terrified of a relapse. I was comforted by your statement earlier but I haven't felt great today and am fearful. I'm not really having any C-diff symptoms but I don't want any either. I am taking the probiotics that you mentioned. My insides just don't feel very good today and maybe that's because of the post infectious IBS I was left with from the horrible C-diff back in February. I know I have to stay the course but if you have any words of reassurance or any other guidance, I'd appreciate it. Thank you. Jacque

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Just now saw your post from Oct 10, 2021 - How did it go? In 2011 my Periodontist put me on Amoxicillin for 10 days and on the 10th day I got the famous diarrhea. Two days later I was recovered in the hospital for C-difficile. From what I understand all broad -based antibiotics pose a problem for c-diff. And Amoxicillin falls into that category and is known to cause c-diff. I have not taken antibiotics since. Thankfully, have not needed. I had a Dermatologist who wanted to give me an antibiotic for MOHs procedure, but I refused. I told the Dermatologist who had referred me, and she gave me an antibiotic cream to put on the site and I was fine

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