Anyone taken Evenity (romosozumab) for Osteoporosis?

Posted by arlene7 @arlene7, May 27, 2020

Has anyone taken Evenity? I understand it’s only been on the market for a little over a year. I’m hoping it will help with my severe osteoporosis. Any information is helpful.

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

Update - my cardiologist told me no Evenity for me. I have heart issues. He said I was ok to try Tymlos.

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@lillea

Saz, hope you will continue to post as you begin Evenity. I should be a month or so behind you. Really hope it will help you... have you discussed with your doctor what to follow up with yet?

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Sure! Really hope it will help you too.
My doctor said that it is too soon to discuss. One year is long and I am confident on new researches.

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@elisabethv

Hi, i am Elisabeth from Long Island. I am new to this conversation. I will have my 3rd Evenity injection on Tuesday. It left my arms quite sore as well. After 2 days I was fine. I am 59 and was concerned about the risks and so I spoke to my cardiologist before starting.

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So I was told to massauge the spot where you received ur needle right afterwards. It works

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So I will be receiving my 5th Evenity shot next week. My only change has been my blood work. Since being on Evenity I had my Comprehensive Metabolic Panel done. It shows, only since being on Evenity, that my Alkaline Phosphatase, S has been elevated. It is a high 192. Has anyone had any labs done? If so, has anyone seen any elevation on their Alkaline Phosphatase S while being on Evenity?

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@dee5

Update - my cardiologist told me no Evenity for me. I have heart issues. He said I was ok to try Tymlos.

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Two of my cardiologists preferred Evenity to Tymlos due to my afib. ( I did Tymlos anyway with support of endo).

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@windyshores

Two of my cardiologists preferred Evenity to Tymlos due to my afib. ( I did Tymlos anyway with support of endo).

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I think it depends on the specifics of the heart problem. I have a congenital heart problem. My cardiologist gave the OK to both one year and two years of Evenity. But that is specific to me, not everyone or every heart.

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@dmort

Hi! My doctor has prescribed Evenity for my osteoporosis. I’m extremely afraid of the major cardiovascular side effects. Does anyone know how long these major side effects last (i.e. most at risk for 3 days after injection)? Also, why does this medication cause those particular side effects when other osteoporosis medications do not? I’m expecting to get a call soon to set up my first shot so any information would be greatly appreciated.

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I posted elsewhere in the thread along with others regarding heart effects. It depends on the person and the heart condition. I talked to cardiologist who gave the green light. Others with different heart issues got a different answer. So talk with cardiologist.

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@marcd

Evenity can be continued for two years and will continue to benefit bone density according to this report.
https://pubmed.ncbi.nlm.nih.gov/29694685/
The report is based on a study of patients who received Evenity for two years, followed by Prolia after completion of 2 years of Evenity. The report says that bone density continued to increase throughout the the 2 years of Evenity and continued to increase during the following year of treatment with Prolia.
I would be interested in thoughts of others in regard to this possible treatment
I have been taking Evenity for 7 months with no side effects.

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I reviewed the study about continuing Evenity for two years with my endocrinologist. The study is posted here: https://pubmed.ncbi.nlm.nih.gov/29694685/ My endocrinologist wrote me an email that says the following: "Based on the current knowledge I would not favor proceeding directly with a second year of Evenity, but rather switch to an anti-resorbing drug. Having said that, a second Evenity course in the future is a reasonable option. Another alternative is to switch to a cyclical form of therapy, with intervening short courses of Evenity against a background therapy with anti-resorbing agents."
I would appreciate thoughts of anyone who has experience related to this.

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Evenity can be continued for two years and will continue to benefit bone density according to this report.
https://pubmed.ncbi.nlm.nih.gov/29694685/
The report is based on a study of patients who received Evenity for two years, followed by Prolia after completion of 2 years of Evenity. The report says that bone density continued to increase throughout the the 2 years of Evenity and continued to increase during the following year of treatment with Prolia.

I reviewed the study about continuing Evenity for two years with my endocrinologist.

My endocrinologist wrote me an email that says the following: "Based on the current knowledge I would not favor proceeding directly with a second year of Evenity, but rather switch to an anti-resorbing drug. Having said that, a second Evenity course in the future is a reasonable option. Another alternative is to switch to a cyclical form of therapy, with intervening short courses of Evenity against a background therapy with anti-resorbing agents."

I would appreciate thoughts of anyone who has experience related to this.

REPLY
@marcd

Evenity can be continued for two years and will continue to benefit bone density according to this report.
https://pubmed.ncbi.nlm.nih.gov/29694685/
The report is based on a study of patients who received Evenity for two years, followed by Prolia after completion of 2 years of Evenity. The report says that bone density continued to increase throughout the the 2 years of Evenity and continued to increase during the following year of treatment with Prolia.

I reviewed the study about continuing Evenity for two years with my endocrinologist.

My endocrinologist wrote me an email that says the following: "Based on the current knowledge I would not favor proceeding directly with a second year of Evenity, but rather switch to an anti-resorbing drug. Having said that, a second Evenity course in the future is a reasonable option. Another alternative is to switch to a cyclical form of therapy, with intervening short courses of Evenity against a background therapy with anti-resorbing agents."

I would appreciate thoughts of anyone who has experience related to this.

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Thank you for the link. It is already 4 years old. I wonder if there are more recent researches. I have been told today, during my first injection that Evenity was ok for 1 year only and then i should receive Prolia.

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