Unilateral facial swelling - pls help

@gnandanpai Welcome to Mayo Connect . This must be so confusing and frustrating for you. Have you gone to a major medical center or a university teaching hospital? I’m thinking you need someone at a higher level who can put everything together for you. There are many new autoimmune diseases suddenly appearing and most community-based physicians just cant keep up. You can google ‘medical centers of excellence’ in your area as a start. I go to the university teaching hospital about 30 miles away and see a neuroimmunologist because no one locally knew what i had.
You’ve seen quite a few doctors, but have you seen a dermatologist?

Hi there, in answer to your comment on swelling in your face. I have similar problems. My face starts swelling at my temples and goes down into my glands in my throat My face swells. The only thing that makes it go away fast is prednisone. It lasts about 7 to 10 days.. I have been diagnosed with Sjogrens. I’m not convinced though.

@burlingtongirl your face swells and you have sjogren’s. So the swelling didn’t go away with the treatment for sjogren’s? How often does the swelling happen?

@becsbuddy I am already seeing specialists from the best hospitals in NYC (Mt Sinai and NYU Langone). Do you have any other recommendations in the NY and surrounding areas? I am seeing Rheumatology, Ophthalmology and Head & Neck surgery next after getting face & brain MRIs.

@burlingtongirl Did you have dry eyes and a dry mouth? Online it says for Sjorgen's dry eye and dry mouth are the classic/typical symptoms. Looks like your symptoms are bilateral.

@gnandanpai .. It sounds like you have a good team working for you. Are they able to share medical records with each other? If you haven’t already, be sure to start a journal with names, dates, who said what, medications suggested, etc. believe me, it sure helps to have everything years from now.
Have the doctors come up with a plan of care?

@gnandanpai - Welcome to Mayo Connect! This is a very good place to share information and get input from other members with similar problems.
After reading your synopsis I recommend that you do try the treatment recommended by the ENT- antibiotics and prednisone.
Sinusitis, especially chronic, can be difficult to pinpoint. The CT says “polyploid mucosal thickening”.
I have a lifelong history of sinus illness- since childhood. I have had 2 sinus surgeries. Findings at the first procedure was identical to your CT report.
The second surgery just involved some minor corrections.
If you don’t try it, you will never know if there was any change at all.
Will you consider it?

@becsbuddy Yes, I have maintained solid records, synopsis and symptom journal and shared it with every specialist I meet. Some of the specialists are outside the network but I physically give them the notes, labs, imaging etc from other folks

I am not convinced it is sinusitis given I have NO other symptoms. I breathe fine, no headaches, no congestion, no pain, no snoring. The mucosal thickening I have been told is within normal levels for the season (I had a cold episode a few weeks prior).

I have dealt with this on and off for 4 years. Dermatologist had me on prednisone, got Prednisone rosacea. Use all hypoallergenic products. Face swells, hot, red blotches eyes, nose chin, neck. Like a sunburn, extra dry. Cream makes it worse. only relief is ice paks. Prednisone shots helped once , not anymore. Keflex helped once and not anymore. No answers from anyone. I am currently looking into hereditary angioadema. Has anyone experienced this?

Hi @fisherslady and welcome to Mayo Clinic Connect. You'll see that I moved your post to a discussion talking about facial swelling.
There is also another discussion going on here: Facial Swelling - no diagnosis after 2 years:https://connect.mayoclinic.org/discussion/facial-swelling-no-diagnosis-after-2-years/

Are you currently keeping a log of when it flares up? Have you noticed any consistencies?