1. < Digestive Health
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Side effects with omeprazole/Prilosec use

Posted by blueorca @blueorca, May 5, 2018

i am an 18-year user of daily OTC Prilosec. It does a perfect job of controlling my GERD but I am constantly battling side effects of nutritional deficiencies in iron, B-12, magnesium, etc. For example, my hair is extremely thin and loss of energy is a constant problem. I am looking for specific help in knowing which supplements to take for this and in what doses and formats and on what schedule. All the nutritionists I've found locally are not well-versed in Prilosec use. Is there a medical provider out there who specializes in this? And would they be willing to work with me long distance?

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Profile picture for 2cents
2cents | @2cents | Jan 12, 2022
In reply to @kanaazpereira "Hi @nightngale1998 and members in this discussion, I thought you might be interested in reading this..." + (show)
Profile picture for Kanaaz Pereira, Connect Moderator @kanaazpereira

Hi @nightngale1998 and members in this discussion,

I thought you might be interested in reading this recent article published in the journal of Gastroenterology:
– https://www.gastrojournal.org/article/S0016-5085(17)35623-8/fulltext

Based upon numerous studies which evaluated the long-term use of PPIs like Omeprazole, researchers conclude that (copied):

– Despite the recent alarm generated by some high-profile, newsworthy publications, few (if any) of the recent scare stories have attempted to balance the benefits of PPIs with their alleged risks.
– A great number of patients are receiving PPIs unnecessarily for conditions or symptoms for which they would not have been expected to provide benefit. Furthermore, many patients who are on PPI treatment for appropriate indications are receiving excessively high daily doses.
– For some patients, treatment may need to be lifelong. However, multiple “false alarms” related to the safety of PPIs could ultimately lead to inappropriate discontinuation of treatment with potentially serious consequences for some patients.
– Much of the current evidence linking PPI use to serious long-term adverse consequences is weak and insubstantial. It should not deter prescribers from using appropriate doses of PPIs for appropriate indications.

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I wanted to mention that Omeprazole was prescribed for me for several years by a physician. Endoscopy had shown eosinophilic, and Barrett's cells. There was reflux, and a hernia. This was bumped up to a higher dose, but really didn't help that much. A couple years later I happened to have a genetic test that was needed to determine how I metabolized certain drugs. The results came out that I was a very fast metabolizer. Omeprazole was one of the drugs that was affected by this genetic condition. I was told to switch to another PPI since I'd never get relief with the Omeprazole.

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2cents | @2cents | Jan 12, 2022
In reply to @2cents "I wanted to mention that Omeprazole was prescribed for me for several years by a physician...." + (show)
Profile picture for 2cents @2cents

I wanted to mention that Omeprazole was prescribed for me for several years by a physician. Endoscopy had shown eosinophilic, and Barrett's cells. There was reflux, and a hernia. This was bumped up to a higher dose, but really didn't help that much. A couple years later I happened to have a genetic test that was needed to determine how I metabolized certain drugs. The results came out that I was a very fast metabolizer. Omeprazole was one of the drugs that was affected by this genetic condition. I was told to switch to another PPI since I'd never get relief with the Omeprazole.

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CYP2C19 was the name of the test a cardiologist ran for a cardiology medication. I was an ultra-fast metabolizer, but I don't think many know about what it's used for.

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thellman | @thellman | Jan 13, 2022
In reply to @nightngale1998 "Hi there: Has anyone had success in weaning off of Omeprazole? I take it for GERD...." + (show)
Profile picture for Bonnie @nightngale1998

Hi there: Has anyone had success in weaning off of Omeprazole? I take it for GERD. Thank you in advance!

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Probiotics taken daily.

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murphy1231213 | @murphy1231213 | Jan 14, 2022
In reply to @nightngale1998 "Hi there: Has anyone had success in weaning off of Omeprazole? I take it for GERD...." + (show)
Profile picture for Bonnie @nightngale1998

Hi there: Has anyone had success in weaning off of Omeprazole? I take it for GERD. Thank you in advance!

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I took 20 mg of omeprazole once a day for at least 5 years plus. I asked my doctor to reduce it to 10 mg and all went well for 6 months. I read about a product that others had success with, so I tried it, IBS Clear. I took to with my omeprazole for a week and then took my omeprazole every other day for a week and then stopped. All is good and haven’t taken the omeprazole for 3 weeks now. I do take multidopholis (pro and prebiotic) every morning. I drink 4 oz of water with1/4 tsp of baking soda every night about an hour after I eat.

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dianecostella | @dianecostella | Jan 14, 2022
In reply to @nightngale1998 "Hi there: Has anyone had success in weaning off of Omeprazole? I take it for GERD...." + (show)
Profile picture for Bonnie @nightngale1998

Hi there: Has anyone had success in weaning off of Omeprazole? I take it for GERD. Thank you in advance!

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I was on it for years. I had Fundoplacation surgery and just stopped taking it. I was fine no side effects.

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chrism99 | @chrism99 | Jan 14, 2022
In reply to @nightngale1998 "Hi there: Has anyone had success in weaning off of Omeprazole? I take it for GERD...." + (show)
Profile picture for Bonnie @nightngale1998

Hi there: Has anyone had success in weaning off of Omeprazole? I take it for GERD. Thank you in advance!

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6 months on on either omeprazole or Protonix. Stuff gave me low energy and generally sick feeling in my stomach. Went off cold turkey with no side effects and felt better. Now use ginger and enzyme supplements daily.

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pjbcorsi1955 | @pjbcorsi1955 | Jan 14, 2022
In reply to @murphy1231213 "I took 20 mg of omeprazole once a day for at least 5 years plus. I..." + (show)
Profile picture for murphy1231213 @murphy1231213

I took 20 mg of omeprazole once a day for at least 5 years plus. I asked my doctor to reduce it to 10 mg and all went well for 6 months. I read about a product that others had success with, so I tried it, IBS Clear. I took to with my omeprazole for a week and then took my omeprazole every other day for a week and then stopped. All is good and haven’t taken the omeprazole for 3 weeks now. I do take multidopholis (pro and prebiotic) every morning. I drink 4 oz of water with1/4 tsp of baking soda every night about an hour after I eat.

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Were you taking omeprazol for GERD?
You substituted the IBS clear for omeprazol for GERD medication?

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Profile picture for murphy1231213
murphy1231213 | @murphy1231213 | Jan 14, 2022
In reply to @nightngale1998 "Hi there: Has anyone had success in weaning off of Omeprazole? I take it for GERD...." + (show)
Profile picture for Bonnie @nightngale1998

Hi there: Has anyone had success in weaning off of Omeprazole? I take it for GERD. Thank you in advance!

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Yes

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rashida | @rashida | Jan 15, 2022
In reply to @dandl48 "Wouldn't taking vinegar increase your GERD since it is an acid? I take 4 generic Nexiums..." + (show)
Profile picture for dandl48 Dave @dandl48

Wouldn't taking vinegar increase your GERD since it is an acid? I take 4 generic Nexiums plus a Zantac along with D3 and magnesium. My blood work is fine.

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@dandi apple cider vinegar exacerbates my GERD too.

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Profile picture for dandl48 Dave
dandl48 Dave | @dandl48 | Jan 15, 2022
In reply to @nightngale1998 "Hi there: Has anyone had success in weaning off of Omeprazole? I take it for GERD...." + (show)
Profile picture for Bonnie @nightngale1998

Hi there: Has anyone had success in weaning off of Omeprazole? I take it for GERD. Thank you in advance!

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Wow, this is an old post. No longer taking Zantac since it is reported that it causes cancer, at least the old formulation did.

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