Side effects with omeprazole/Prilosec use

Posted by blueorca @blueorca, May 5, 2018

i am an 18-year user of daily OTC Prilosec. It does a perfect job of controlling my GERD but I am constantly battling side effects of nutritional deficiencies in iron, B-12, magnesium, etc. For example, my hair is extremely thin and loss of energy is a constant problem. I am looking for specific help in knowing which supplements to take for this and in what doses and formats and on what schedule. All the nutritionists I've found locally are not well-versed in Prilosec use. Is there a medical provider out there who specializes in this? And would they be willing to work with me long distance?

Interested in more discussions like this? Go to the Digestive Health Support Group.

Profile picture for JK @contentandwell

@beckymel I feel negligent because it has somehow escaped me that my levothyroxine could be contributing to my osteoporosis as could the omeprazole that I took for several years. I am also on prednisone which is a major cause of osteoporosis so I attributed it to that.

I started doing Tymlos injections a couple of weeks ago because my osteoporosis has gotten quite advanced. Unfortunately, there is no drug for osteoporosis without side effects, but I think that's true of all drugs. From what I have heard the percentage of people on drugs for osteoporosis who have serious side-effects are in a small minority.

I guess we all just have to forge ahead with hopes we will not be a part of that small minority with serious side-effects.
JK

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Hi JK,
I am on Omeprezole and Prednisone. I also have been told that I need to take Tymlos. Can I ask how the Tymlos treatment is going for you? I'm a little nervous about the side effects. Did you have any? If so how long? Any suggestions for me would be appreciated. I understand that it is a new drug and there isn't a lot of people who take it so your response is valuable. I also understand that everyone is different with different medications and conditions.

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Profile picture for daisymae53 @daisymae53

Hi JK,
I am on Omeprezole and Prednisone. I also have been told that I need to take Tymlos. Can I ask how the Tymlos treatment is going for you? I'm a little nervous about the side effects. Did you have any? If so how long? Any suggestions for me would be appreciated. I understand that it is a new drug and there isn't a lot of people who take it so your response is valuable. I also understand that everyone is different with different medications and conditions.

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Hi, @daisymae53 Welcome to Connect!

I am almost done with Tymlos. I will finish at the end of the year or the beginning of 2023 depending on when my pen runs out. That will be 22 or 23 months of Tymlos, a month shorter than the full 24 months. I am doing that because my deductible is huge the first month of the year and my endocrinologist said that getting off a month or two early wouldn't make much difference.

The most common effect seems to be fluid retention in the belly area. I presume it must be a defense response of the body to all of the little injections. The injections are either painless or just a minor twinge. I hope my belly will go down somewhat when I get off of it. The other side effect that seems relatively common is achy muscles and/or joints. I find that comes and goes. For a brief period, it was bothering me a lot but now it is not. Initially I had no side effects, but the achy legs and puffy belly developed over time. A small number of people do have more difficult side effects but then they generally reduce their dosage and increase it as their body adjusts to Tymlos. I asked my endocrinologist if I should start low and she said no, and as it turned out I had no side effects initially so that was the correct way to go.

Many people do find it affects their blood pressure. Mine was slightly high and is not now so perhaps that's due to Tymlos.

I am no longer on either Omeprazole or prednisone. When I realized that Omeprazole could have an effect on your bones due to blocking the absorption of some nutrients I asked to be changed to something else so I am on Famotidine now which is the same as Pepcid AC.

Before you start make an in-person or phone appointment with a clinical advisor about injecting and also go to the Tymlos site and print out the diagram to help you keep track of where you have injected so you are not injecting in the same place all of the time. You can also get a free travel case for the pen with slots for 7 days of needles. If you do travel at all that's very nice to have.
JK

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Profile picture for Bonnie @nightngale1998

Hi there: Has anyone had success in weaning off of Omeprazole? I take it for GERD. Thank you in advance!

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Tymlos is a hormone treatment that is very effective in preventing spinal fractures by speeding up the building of bone. Caused cancer in lab rats (high doses). I've had success building bone by getting my Vit D up to snuff, following recommendations at saveourbones.com, eating prunes, taking Ca and some strontium. I quit Omparazole then Nexium after I learned about effects of PPIs on the kidney. I find that gargling with 8.8 pH alkaline water helps my throat, which is prone to irritation from GERD resulting from my hiatal hernia. The alkalinity neutralizes pepsin, the enzyme that digests protein and can also digest throat tissue. (I learned of this via a journal article from PubMed.) I also try to finish eating at least 4 hours before bedtime, use Gaviscon Advance aniseed suspension as a stomach block and antacid. My go-to antacid is Life Extension's Esophacool.

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Profile picture for Bonnie @nightngale1998

Hi there: Has anyone had success in weaning off of Omeprazole? I take it for GERD. Thank you in advance!

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If you have fm you should not eat sugars of any kind , dairy or wheat.

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Profile picture for quantumgreen @quantumgreen

Tymlos is a hormone treatment that is very effective in preventing spinal fractures by speeding up the building of bone. Caused cancer in lab rats (high doses). I've had success building bone by getting my Vit D up to snuff, following recommendations at saveourbones.com, eating prunes, taking Ca and some strontium. I quit Omparazole then Nexium after I learned about effects of PPIs on the kidney. I find that gargling with 8.8 pH alkaline water helps my throat, which is prone to irritation from GERD resulting from my hiatal hernia. The alkalinity neutralizes pepsin, the enzyme that digests protein and can also digest throat tissue. (I learned of this via a journal article from PubMed.) I also try to finish eating at least 4 hours before bedtime, use Gaviscon Advance aniseed suspension as a stomach block and antacid. My go-to antacid is Life Extension's Esophacool.

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I’m curious about the alkaline water and Life Extension's Esophacool. I never had issues before, until I finished chemo last year. Now it seems I have GERD symptoms. My GI dr told me to take Pepcid as needed, but I’m finding I need it almost daily now. I don’t eat fried foods.
Thanks

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Hi,I’ve been on omeprazole for a year because of stubborn reflux issues caused by another medication.About 5 months ago I started getting bowel cramps and had to run to the toilet several times a day. I read that Omeprazole can cause bowel inflammation and some tests did show mild inflammation of my bowel, so I halfed the dosage of Omeprazole.My bowel issues calmed down but I never fully recovered. Recently it got worse again and I did more tests and I was diagnosed with IBD.I’m still on 10mg of Omeprazole and tried to explain to my dr that I think they might have caused this but he didn’t seem interested.Do you guys think my IBD might improve if I get off the Omeprazole or is the damage already done?

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Profile picture for lilybell @lilybell

Hi,I’ve been on omeprazole for a year because of stubborn reflux issues caused by another medication.About 5 months ago I started getting bowel cramps and had to run to the toilet several times a day. I read that Omeprazole can cause bowel inflammation and some tests did show mild inflammation of my bowel, so I halfed the dosage of Omeprazole.My bowel issues calmed down but I never fully recovered. Recently it got worse again and I did more tests and I was diagnosed with IBD.I’m still on 10mg of Omeprazole and tried to explain to my dr that I think they might have caused this but he didn’t seem interested.Do you guys think my IBD might improve if I get off the Omeprazole or is the damage already done?

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Time will tell. You can't do more.
I have been on omo for years and the past two years having extremely loose stools three times a day. Many, many test brought up nothing. Finely I received a test whare as my liver number was up. So I took a chance and am taking it only once a day and after some time it seems to be much better so far. Hang in there and stay tuned.

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Profile picture for lilybell @lilybell

Hi,I’ve been on omeprazole for a year because of stubborn reflux issues caused by another medication.About 5 months ago I started getting bowel cramps and had to run to the toilet several times a day. I read that Omeprazole can cause bowel inflammation and some tests did show mild inflammation of my bowel, so I halfed the dosage of Omeprazole.My bowel issues calmed down but I never fully recovered. Recently it got worse again and I did more tests and I was diagnosed with IBD.I’m still on 10mg of Omeprazole and tried to explain to my dr that I think they might have caused this but he didn’t seem interested.Do you guys think my IBD might improve if I get off the Omeprazole or is the damage already done?

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My understanding is you cannot be on it for a long time. My doctor just put me on it and said only for a month. You should research this and ask your doctor or get another opinion.

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Profile picture for lilybell @lilybell

Hi,I’ve been on omeprazole for a year because of stubborn reflux issues caused by another medication.About 5 months ago I started getting bowel cramps and had to run to the toilet several times a day. I read that Omeprazole can cause bowel inflammation and some tests did show mild inflammation of my bowel, so I halfed the dosage of Omeprazole.My bowel issues calmed down but I never fully recovered. Recently it got worse again and I did more tests and I was diagnosed with IBD.I’m still on 10mg of Omeprazole and tried to explain to my dr that I think they might have caused this but he didn’t seem interested.Do you guys think my IBD might improve if I get off the Omeprazole or is the damage already done?

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Been there. Dangers of not using omo were greater than the gerd itself.

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Profile picture for Jackie, Alumna Mentor @travelgirl

@nightngale1998 I been on Omprazole for 2 1/2 yrs. I go on and off myself . Mostly cause I forget to take it. My usual dose is 40mg in the AM and 40mg in the PM. I can go for about 30 days without taking it. Then BAM. The stabbing chest pains, sore throat and stomach starts to hurt. So I have to go back to regularly taking the pills. It usually takes about 2 weeks to get back to feeling normal no chest pains and such.

I tried the vinegar once.. OMG.. I might as well drank boric acid, it felt about the same. It was like flames were shooting down my throat. I think that works for people with occasional acid reflux?

You have to completely live on a bland diet. Which is impossible for me at least. I think in order to live without the medicine. But i don't even know, if that works when you have a hernia?

My blood work is fine perfect actually after this long. I think it can possibly cause issues with our kidney's?? But I don't know anyone who has been affected that way?

Now I have a couple of family members who have been taking this medicine for 20+ years and they are fine today in their 70"s.

If I am not mistaken Gerd is the precursor to Barrett's Syndrome? Barrett's Syndrome is the precursor to Throat Cancer? My Uncle has barrett's Syndrome and the Dr's watch him like a hawk.

I would talk to your DR again or go for another opinion to see what another Dr recommends for you. You may hear a different story.

I wish you the Best..
Jackie

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Thanks to my gerd. I have severe swallowing issue, barrettes esophagus, damaged vocal cords, chronic cough, delayed gastric emptying… getting my insurance to cover gastric bypass has been hell.. and stage 4 on barrettes

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