1. < Osteoporosis & Bone Health

Anyone taken Evenity (romosozumab) for Osteoporosis?

Posted by arlene7 @arlene7, May 27, 2020

Has anyone taken Evenity? I understand it’s only been on the market for a little over a year. I’m hoping it will help with my severe osteoporosis. Any information is helpful.

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windyshores | @windyshores | Dec 15, 2021
In reply to @marcd "Thank you Windyshores... your comment may be correct, in which case I wish I had known..." + (show)
@marcd

Thank you Windyshores... your comment may be correct, in which case I wish I had known this 8 months ago. Nevertheless, maintaining the gains of Evenity by using Forteo still might have advantages. First, maybe the forteo would continue to build bone. Second, unlike the biphosphonates which tend to freeze everything, the forteo would not freeze everything. That might allow a better chance of re-building bone through exercise programs such as weight lifting. You're right, I need to talk with a doc. But meanwhile other's experiences help me understand the possibilities. Thanks again.

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I honestly think they don't know. Evenity is so new. And docs rely on studies. My doc, at a top hospital, didn't seem to know about following Tymlos with Evenity. I learned about that on a forum! ps you are lucky you can lift weights...with fractures I can barely lift a seltzer bottle!

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marcd | @marcd | Dec 15, 2021

Thanks again for your help and encouragement.

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windyshores | @windyshores | Dec 16, 2021
In reply to @marcd "Thank you Windyshores... your comment may be correct, in which case I wish I had known..." + (show)
@marcd

Thank you Windyshores... your comment may be correct, in which case I wish I had known this 8 months ago. Nevertheless, maintaining the gains of Evenity by using Forteo still might have advantages. First, maybe the forteo would continue to build bone. Second, unlike the biphosphonates which tend to freeze everything, the forteo would not freeze everything. That might allow a better chance of re-building bone through exercise programs such as weight lifting. You're right, I need to talk with a doc. But meanwhile other's experiences help me understand the possibilities. Thanks again.

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I would like to know what your doc says!

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dedehans | @dedehans | Dec 16, 2021

Evenity is a bionosphosphate like Prolia, Fosamax and one bad side effect is necrosis of the jaw. I have had dental work $$$$ and not about to take a drug that could make me lose my teeth......

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1 reply
bkour | @bkour | Dec 17, 2021

Changing the subject, is the usual protocol to have a shot given in each arm when the drug is administered?

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1 reply
windyshores | @windyshores | Dec 17, 2021
In reply to @dedehans "Evenity is a bionosphosphate like Prolia, Fosamax and one bad side effect is necrosis of the..." + (show)
@dedehans

Evenity is a bionosphosphate like Prolia, Fosamax and one bad side effect is necrosis of the jaw. I have had dental work $$$$ and not about to take a drug that could make me lose my teeth......

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Evenity is not a biphosphanate. It mainly grows bone, but suppresses turnover at a rate less than the biphosphanates or Prolia. Evvenity works by suppressing sclerostin. (For that matter, Prolia is not a biphosphanate either.) The danger of losing your teeth is very very very small with Evenity. The danger of fracture may be high, at least for some. You take it for a year and it turbocharges bone growth.

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1 reply
iowagal | @iowagal | Dec 17, 2021

I have been on Evenity since last April. It can only be taken for 1 year. So far, the only side effect I have had is site swelling and itching. I will have another dexascan in March.

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1 reply
sus34 | @sus34 | Dec 17, 2021
In reply to @windyshores "Evenity is not a biphosphanate. It mainly grows bone, but suppresses turnover at a rate less..." + (show)
@windyshores

Evenity is not a biphosphanate. It mainly grows bone, but suppresses turnover at a rate less than the biphosphanates or Prolia. Evvenity works by suppressing sclerostin. (For that matter, Prolia is not a biphosphanate either.) The danger of losing your teeth is very very very small with Evenity. The danger of fracture may be high, at least for some. You take it for a year and it turbocharges bone growth.

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Great clarification. Do you have any info on why the risk of fracture is high for some or can point me in the direction of related documentation? Would like to understand what makes someone more at risk for fracture. So the bottom line is whether Evenity can grow bone faster than the turnover rate of bone in an individual’s body. Thanks

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1 reply
iowagal | @iowagal | Dec 17, 2021
In reply to @bkour "Changing the subject, is the usual protocol to have a shot given in each arm when..." + (show)
@bkour

Changing the subject, is the usual protocol to have a shot given in each arm when the drug is administered?

Jump to this post

2 shots are given each month.

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windyshores | @windyshores | Dec 17, 2021
In reply to @sus34 "Great clarification. Do you have any info on why the risk of fracture is high for..." + (show)
@sus34

Great clarification. Do you have any info on why the risk of fracture is high for some or can point me in the direction of related documentation? Would like to understand what makes someone more at risk for fracture. So the bottom line is whether Evenity can grow bone faster than the turnover rate of bone in an individual’s body. Thanks

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Fracture risk grows on biphosphanates and Prolia with the length of time on the drug, mostly after 5 years. I don't understand your "bottom line is whether Evenity can grow bone fast then the turnover rate of bone in an individual's body." Evenity grows bone the fastest of any drug and also suppresses turnover.

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