Adrenaline spikes: Med detective needed, award given

Posted by sierrawoods @sierrawoods, Feb 20, 2018

I'm desperate for help. If I was rich, I'd pay a million $ to get answers. It's hard to summarize: I am a 59 yr old woman. 8 yrs ago I started having what feels like strong adrenaline rushes during the night and especially in the early morning. They disrupt my sleep making me severely sleep deprived. It used to happen a few times a month but in the last year, has been happening daily. This is not as simple as anxiety. My life is not particularly stressful compared to years ago and I've always handled stress well. Physical symptoms come first, then anxiety from adrenaline comes after. On rare days, If I sleep through the night, I wake with excess adrenaline and will be hyper the whole day and evening. Sometimes, I will have a severe "crash" in the afternoon with all kinds of symptoms that have me couch-bound. I take a tiny dose of Amitriptyline (10 mg) before bed to help with sleep, but it's obviously not working well enough. I am on Synthroid for non-Hashimoto's Hypothyroidism since 1996. Despite being 59 yrs old, I am not yet officially in menopause (last period was May 2017). TSH, fT4, fT3 are normal. Urine catecholamines (epinephrine & norepinephrine) are normal (although that does not necessarily reflect what is in the brain). Plasma ACTH is normal. I've tested negative for autoimmune disorders. Cortisol was high a few years ago (34.3 mcg/dL) but it's currently high-normal. DHEAS normal. Accompanying the start of this was phantosmia and occasional RLS. My diet is excellent, including a few good supplements. Until last yr when it started happening daily, I was exercising 6 days/wk. I cannot tolerate it any more - any exercise beyond mild cardio/aerobic causes an increase in symptoms. I meditate and have tried all kinds of herbal teas. I've experimented with different possible solutions, to no avail. I'm a voracious researcher (only legit sites) and still cannot figure this out. I'm normally a positive, active, happy person who loves to help others but this is ruining my life. I cannot make any plans, cannot get my work done, cannot even visit friends. I had to stop my volunteer work with children. šŸ™ I'm starting to become depressed and hopeless. I've been to a total of about 9 doctors about this problem and they just shrug their shoulders and send me hope with more disappointment. The only help offered was an addictive prescription for benzos but I refuse to be treated for something without knowing the cause. Ideas: an atypical tumor on my pituitary or adrenal glands? Maybe, but I can't get a doctor to order the necessary MRIs. Perhaps not endocrine but a sleep disorder? High A.M. adrenaline is typical for sleep apnea but it should not cause these severe symptoms, and I really do not think I have sleep apnea (I don't have other symptoms). A neurological disorder? Maybe, but I can't get a doctor to order an MRI of my brain to make sure my pituitary gland is okay. If you've gotten through this far and you have any thoughts, please chime in. If your idea leads to a proper diagnosis and I get well (or treated properly) I will be your slave for life šŸ˜‰ Okay, seriously. I'm not in a good place right now.

Interested in more discussions like this? Go to the Diabetes & Endocrine System Support Group.

Concerning the apnea. I didn't have a clue I had it. I was getting up a few times nightly ostensibly to use the toilet, but if that was a symptom I didn't note it as such. Then, I was tasked with a 5 plus hour drive and suddenly I was so tired an hour and a half in I had to stop at a rest area to take a nap. How strange is that? I had been previously going about my day unaware of any specific feelings of tiredness. Well, that was a wake up call. Something was wrong and I took a sleep study which showed I needed a CPAP machine. The first night I used it I slept through the night. Sleep studies are expensive. I was told I needed to take a $1200 study when I needed a new machine. But I refused to be whipped around by the established powers that be and purchased my own machine on Amazon. Don't know for sure if they still have, but if you are an accomplished researcher you may be able to find one and try out. You said you would spend a million. if you had it. This would not cost a million but still requires willingness to spend a bit if you want to give that a try. Who knows if any issues will be resolved but at least you can cross that one off your list.

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@krisjb1

Have to ask you if finding a dr. to prescribe Cytomel has been an issue. My endocrinologist and 2 GP's said "No" to cytomel despite my reverse T3 being high (showing that the T4 generated through use of T4 is not undergoing conversion) or T3 is not being accepted into cells). Explanation was that the Endocrinology board only recommends dr.'s use Synthroid.

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Yes, I did have a hard time with my own doctor, but a walk-in clinic doctor actually prescribed Cytomel the first time based on bloodwork, and then an endocrinologist chose to continue it for me. It was a life-changer! So thankful that I found a doctor who believed in it.

Another option is to find a naturopathic doctor who can prescribe desiccated thyroid because it has both T3 and T4, so it may help youā€¦

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@libjen

Yes, I did have a hard time with my own doctor, but a walk-in clinic doctor actually prescribed Cytomel the first time based on bloodwork, and then an endocrinologist chose to continue it for me. It was a life-changer! So thankful that I found a doctor who believed in it.

Another option is to find a naturopathic doctor who can prescribe desiccated thyroid because it has both T3 and T4, so it may help youā€¦

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Thanks. I guess it is going to be based on luck at finding the right person to prescribe.

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Last night it just came to me that you may have an issue with electromagnetic pollution. My bed is on the second story and my modem and router are in a closet directly beneath it on the first floor. Despite taking many supplements and treating sleep apnea I had not been getting much rest for years. About 6 months ago I put both modem and router on a timer so that they are off during my sleep hours. This change has made a big improvement in my sleep pattern. There are still nights that I have sleep issues due to anxiety and life experiences, but there are also nights where I sleep through which is very unique. You may want to consider removing that possible source of sleep disruption. It could easily be overlooked.

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Has anyone had any luck with figuring out the adrenaline surges that wake you up in the early morning?

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Hey all šŸ™‚

Just joining in on the thread. I've had similar issues with adrenaline rushes since last summer (and coincidentally after my second covid vaccine?) . I'm 32 years old, have always had anxiety which is why I can tell this is very much a different beast.

Similar story, been waking up to adrenaline rushes and increased heartrate. I also have exercise intolerance, tiredness, brain fog, thermal irregularities and muscle twitches and weird buzzing sensation in my body.

Been to the ER etc, they say I'm healthy and it is just anxiety. I'm on SSRIs and have been on and off for years. Beta blockers helped me a little, but since I have already very low blood pressure, I couldn't continue taking them. They would also bring my resting HR to the 40's which is very unpleasant, so I stopped using them.

I started taking salt tablets that have potassium in them to help with the BP a bit and have continued taking them. I stopped waking up at night and started feeling a lot better.

Last month I had one day where I experienced the adrenaline rush while walking my dog in the morning - the only thing different was that I had a glass of wine the night before (I haven't had any alcohol in around 6months or so due to the issues I've been having).

This morning I also had the adrenaline rush after I got out of bed to go to work at 5am. Called in sick, had some juice and a salt tablet. Only thing different was that last night I took ibuprofen for a slight headache.

My hunch is something to do with potassium/BP/autonomic dysfunction... All I can say is that i think the salt&potassium tablets have helped me. If I was brave enough to experiment, I would try to be without them for a month and see if things deteriorate quickly but for now, I need to be able to go to work :/

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@veeravee

Hey all šŸ™‚

Just joining in on the thread. I've had similar issues with adrenaline rushes since last summer (and coincidentally after my second covid vaccine?) . I'm 32 years old, have always had anxiety which is why I can tell this is very much a different beast.

Similar story, been waking up to adrenaline rushes and increased heartrate. I also have exercise intolerance, tiredness, brain fog, thermal irregularities and muscle twitches and weird buzzing sensation in my body.

Been to the ER etc, they say I'm healthy and it is just anxiety. I'm on SSRIs and have been on and off for years. Beta blockers helped me a little, but since I have already very low blood pressure, I couldn't continue taking them. They would also bring my resting HR to the 40's which is very unpleasant, so I stopped using them.

I started taking salt tablets that have potassium in them to help with the BP a bit and have continued taking them. I stopped waking up at night and started feeling a lot better.

Last month I had one day where I experienced the adrenaline rush while walking my dog in the morning - the only thing different was that I had a glass of wine the night before (I haven't had any alcohol in around 6months or so due to the issues I've been having).

This morning I also had the adrenaline rush after I got out of bed to go to work at 5am. Called in sick, had some juice and a salt tablet. Only thing different was that last night I took ibuprofen for a slight headache.

My hunch is something to do with potassium/BP/autonomic dysfunction... All I can say is that i think the salt&potassium tablets have helped me. If I was brave enough to experiment, I would try to be without them for a month and see if things deteriorate quickly but for now, I need to be able to go to work :/

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@veeravee Welcome to Connect. Weā€™re a large group patients, caregivers and friends who try to help each other. The first thing i would ask, is have you seen a doctor? Emergency room doctors arenā€™t really equipped to deal with issues such as yours. Your family doctor should be able to do blood work and tests to see if your body is working correctly and to help you if its not.
Did a doctor tell you to take the salt tablets with potassium? Unless the pills were prescribed, i would strongly suggest that you not use them. Any imbalance in the amounts of potassium in your blood can be lethal. (As a nurse, i used to work on a cardiac unit)
Do you think you can call for an appointment tomorrow to see your doctor?

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@becsbuddy

@veeravee Welcome to Connect. Weā€™re a large group patients, caregivers and friends who try to help each other. The first thing i would ask, is have you seen a doctor? Emergency room doctors arenā€™t really equipped to deal with issues such as yours. Your family doctor should be able to do blood work and tests to see if your body is working correctly and to help you if its not.
Did a doctor tell you to take the salt tablets with potassium? Unless the pills were prescribed, i would strongly suggest that you not use them. Any imbalance in the amounts of potassium in your blood can be lethal. (As a nurse, i used to work on a cardiac unit)
Do you think you can call for an appointment tomorrow to see your doctor?

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Thank you for your reply!

A doctor has said I can take a tablet a day considering it helps with retaining fluid and helps me feel less dizzy from low blood pressure. The amount of potassium is only 50mg per tablet so it's quite little.

I have seen a doctor for general blood work up but not any special tests and my problem is deemed to be anxiety related...

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Hi- I am sorry you are experiencing
this. I have had similar symptoms for 2 months with no answers. Have you heard of POTS? It is something I am also looking into. Best wishes!

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@aae

Hi- I am sorry you are experiencing
this. I have had similar symptoms for 2 months with no answers. Have you heard of POTS? It is something I am also looking into. Best wishes!

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Please read my comment below. Best of luck on your journey to wellness!

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