To all who have replied to my original post, thank you. I've not yet read all articles, but I've come to this conclusion. Long term use of MM is not safe, and can cause reduced cognitive skills, and more importantly for me, loss of memory. I took a neuropsych test last week, and am waiting for the results, but I do know, compared to the same test 2 years ago, that my cognitive skills and memory have declined. So my use of MM to help my RLS and sleep apnea must be temporary, long enough to gradually lower or eliminate my pramipexole intake (a dopamine agonist), so that, when needed again, the dosage is minimal. Thanks again to all your comments. They have helped to relieve my frustration over controlling the severity of my RLS.