Hello @fromlondon5, Welcome to Connect. You will notice that we changed the title of your discussion a little to better describe the topic of your discussion and hopefully bring in members with experience to share. Here is some information you may find helpful until other members share their experience with you.

"The body cannot excrete excess iron, so it stores it in certain organs, notably the liver, heart, and pancreas, which can lead to organ damage. Damage to the ..." --- Iron overload disorder: Symptoms, causes, and treatment: https://www.medicalnewstoday.com/articles/166455

Did your doctor explain why you need to stop taking your iron and vitamin b12 supplements other than the levels are too high?

I can answer about the high B12 as I have a similar situation right now. Elevated B12 in blood can indicate a potential problem with the liver or kidneys, undiagnosed diabetes, or another blood disorder. You are asked to stop all B12 containing supplements for a time to determine whether the high reading is from supplements or your body. 6 months is the typical time to stop supplements.

As for the high iron, John is correct, and those supplements can linger in the fat of the liver for a long time, so supplements must be stopped usually for 6 months to determine what your body is doing.

Eating a healthy diet will provide enough iron and B12 to keep you healthy unles you have some form of anemia. Were the supplements prescribed for you to treat a deficiency?

Sue

I have a low transcobalamin test(Vitamin B12 Binding Capacity, Unsaturated (Transcobalamin)( RESULT NAME RESULT VALUE UNITS REF. RANGE LO - Vitamin B12 Binding 638 pg/mL 650-1340 L Cap Abnormal Flag: L Reference Range: 650-1340) they prescribed sublingual B12 (taking 1000-5000 per day prn depending on numbness).
I asked about my ferritin levels and they were high at 204. I am extremely tired and have ringing in my ears. I have MS, SCAD, and Afib and I take metoprolol tartrate 50mg twice daily and Eliquis 5mg twice daily along with other supplements calcium/mag, and probiotics. I am tired of feeling BAD!! And I don't know where to turn next!!

Hi Colleen,
I would like to get a second opinion at Mayo clinic. How does one even start the process?
With all of my health issues do I send information up to the clinic. I know I have many complex condition but I don't go to the doctor much. I go for yearly follow ups but everyone seems to not really give a hoot or at least that's how I feel, and when I have a new health issue they treat the symptoms but not the root cause.
Are my health issues due to a genetic disorder that my cells have an issue picking up B12 as show by the Vitamin B12 Binding Capacity, Unsaturated (Transcobalamin) B12 Binding 638 pg/mL 650-1340 L Cap Abnormal Flag: L Reference Range: 650-1340) . But why are my other tests folate/B12 are high normal. The supplements are in my blood stream but the cells aren't picking them up correctly?
Thanks,
Pat