@deekay2021 First, welcome to Mayo Clinic Connect. We are fellow patients/caregivers/family members who share our experiences, as you can see from reading the posts here.

Your dilemma sure seems to be familiar with what others have been through, doesn't it? My husband had a cadaver transplant kidney Oct 2016. He still gets bloodwork done every three months, but has had no medication change in several years.

While a transplant can be life-saving, it is also life-changing. Changes in personality, changes in lifestyle, changes in family dynamics. Letting the transplant team know about the changes you see, getting your husband to have a full physical [not always an easy task!], may help everyone understand the differences you see. Have you kept a journal of the changes, are they prominent certain times of the day, after specific activities, etc.? This could help narrow down the issues, for the medical team, and help you see patterns.

You mention you have been married for 36 years. Congratulations! A complete physical for your husband, to rule out other issues going on, would be a great start to figuring this all out. My husband had personality changes also, but we also had other factors going on, like his job, household changes, etc. It's really hard to pin it all on one particular thing when I saw all we were going through.

Please let me know how we can help you today, and if you have thoughts of how you will proceed. Will you do that for me?
Ginger

Deekay, I'd like to add my welcome. How are you doing today?