Sputum tests: Problems producing enough sputum

Posted by Tina Sims @tinaesims, Jul 14, 2020

I have problems producing enough sputum for a sample. I had no problems in March but my doctor wanted it repeated again. Yea... March was negative for MAC and I'm currently on the big 3. I took my sample to the lab this morning and they said there was too much saliva. Any suggestions? Last time I used the nebulizer with saline prior and I also did that this morning.

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@sueinmn

I have always done my samples at home and refrigerated. My doc requires 3 in case one is bad.. They are sent to our department of health lab first, then if positive for NTM they go to NJH for sensitivity testing and complete analysis. My daughter says this is because we have a high presence of TB in our county and they want to be sure the symptoms are from a non-tuberculosis strain of Mycobacteria.

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Wow! I never heard of sending them to the Department of Health lab first. I usually overnight mine to National Jewish. Where do you live? I did not realize TB was even much of an issue anymore.

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@pop55

Wow! I never heard of sending them to the Department of Health lab first. I usually overnight mine to National Jewish. Where do you live? I did not realize TB was even much of an issue anymore.

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I'm in Minnesota - my clinic handles it for me. My county has a large immigrant population as well as a DHS detention center in our jail, so a lot of TB. It always needs to be ruled out first, otherwise it would probably go to NJH immediately.
Sue

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@sueinmn

I'm in Minnesota - my clinic handles it for me. My county has a large immigrant population as well as a DHS detention center in our jail, so a lot of TB. It always needs to be ruled out first, otherwise it would probably go to NJH immediately.
Sue

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How often are you sending a culture? I am sending it every 4 months now and the colony count is all over the place from as high as 200 to a low of 5. So far they have not suggested treatment and I am praying they don't. Luckily, I do not have any symptoms.

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@pop55

How often are you sending a culture? I am sending it every 4 months now and the colony count is all over the place from as high as 200 to a low of 5. So far they have not suggested treatment and I am praying they don't. Luckily, I do not have any symptoms.

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At first every 3 months, then every 6 months, now I was scheduled for December but have an August appointment after my exacerbation so will probably have a culture next month. My docs culture 3 samples at a time to be sure the highs/lows/odd germs are not just contamination.
My last was "less than 50"
Sue

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@sueinmn

Wow, I don't know about anyone else, but I accidentally inhaled some into my nose one day, and that 7% saline burned! I can't imagine rinsing regularly with it because I think it would really irritate the nose and sinuses.

Another thing to remember is that noses are often colonized with NTM, Staph and other bugs and we don't get sick from them. The nose and sinuses, with regular room temperature airflow, just don't offer the same warm moist environment as a poorly functioning lung.

If I were thinking about trying it, I would ask my ENT first. Saline rinses are usually around .5% so 7% would be 14 times stronger.

Let us know what you learn.

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@sueinmn Interesting about your inhaling the 7% through the nose and it burning. I have an Innispire Go and it delivers the saline so fast that it makes me cough terribly (I've also had a chronic cough for 3 years from the 2018 flu) so I inhale it through my nose and it works fine...I have to blow my nose a good bit because it runs a little during the inhalation but I've always wondered if that salt must do some good for the nasal passages. I also use my good ole Drive Power NebUltra that is much slower but I inhale through the mouth on that machine. I'm still amazed, though, at how fast the Innispire Go is and how you must lose as much of the meds as you breathe in but I'm not a scientist so I don't know if my hunch is correct. But I do know whenever I'm in a hurry or don't feel like sitting for a longer time I use the Innispire Go. It's a little spotty on working, though. I wouldn't give it 100% on performance. Sometimes it won't turn on so I have to keep playing with it. Nan

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@pop55

Wow! I never heard of sending them to the Department of Health lab first. I usually overnight mine to National Jewish. Where do you live? I did not realize TB was even much of an issue anymore.

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@pop55 Just out of curiosity, how do you overnight yours directly to National Jewish? Do you have to have a prescription from a doctor to do that? Mine are done at my hospital here locally but I would love to know how to get my samples to NJH instead. I'm in SC. Nan

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@nannette

@sueinmn Interesting about your inhaling the 7% through the nose and it burning. I have an Innispire Go and it delivers the saline so fast that it makes me cough terribly (I've also had a chronic cough for 3 years from the 2018 flu) so I inhale it through my nose and it works fine...I have to blow my nose a good bit because it runs a little during the inhalation but I've always wondered if that salt must do some good for the nasal passages. I also use my good ole Drive Power NebUltra that is much slower but I inhale through the mouth on that machine. I'm still amazed, though, at how fast the Innispire Go is and how you must lose as much of the meds as you breathe in but I'm not a scientist so I don't know if my hunch is correct. But I do know whenever I'm in a hurry or don't feel like sitting for a longer time I use the Innispire Go. It's a little spotty on working, though. I wouldn't give it 100% on performance. Sometimes it won't turn on so I have to keep playing with it. Nan

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Maybe my nose is more sensitive? Any sinus rinse feels awful (not necessarily burning) for me.
Your Innospire Go experience is not unique. My daughter has gone through several before giving up and going back to the older type. I just use nebbing as my equivalent of "Cat paralysis" (cat on lap) mentioned in a different post by some members. Also, I cough up more gunk using a slower machine with deep slow breaths,
Sue

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@nannette

@pop55 Just out of curiosity, how do you overnight yours directly to National Jewish? Do you have to have a prescription from a doctor to do that? Mine are done at my hospital here locally but I would love to know how to get my samples to NJH instead. I'm in SC. Nan

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I saw Dr Huitt at NJ and her office sends me a sputum collection kit to mail in the sputum. I go to the post office and have it sent overnight rather than just through the regular mail.

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Hi Tina @tinaesims after a few months of trewatment with the big 3 drugs, I also couldn't get enough sputum up for testing. Like you all I could do was too much saliva.

But now I use HYPERTONIC saline 6% (or 7%) and that finally works for adequate sputum induction.

In some countries, you cannot buy HYPERTONIC saline in a pharmacy / drug store. But you can order it online. I get it at a discount price from the hospital where I get my TB meds, but my Pulmonologist had to wrtite a special presciption for it.

It's important to do the sputum test very soon after inhaling the 6% Hypertonic saline. Usually for 'dry' people like you or me, the sputum induction effects of inhaling don't last for very long, so we need to get onto it straight after our inhalations.

All the best, Annie

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@heathert

@toni1132 I think the nose and sinus possibly could show MAC when our lungs have MAC, what comes from my nose is the same colour that comes from my lungs. Not sure that they have tested this yet. Take care Heather

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I never knew this !!! I didn't know MAC can be harbored in the nose/sinuses also! But that seems logical, of course! Thank you for this info, Heather !

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