Where and when did you receive your diagnoses of interstitial Lung Disease and Rheumatoid Arthritis? My husband has antisynthetase and these are two of the immune diseases that are part of it. Antisynthetase Syndrome affects the complete body. Don's started in the lungs but he has also had the blood affected and his muscles. Currently he only has problems with his feet. He doesn't have diabetes but he does have neuropathy of his feet.