Yes, I have taken it. I didn't have an adverse reaction but I stopped taking it and I don't remember why. I took much less than the label said. I put it in the bottom of a glass and filled the glass with water and drank what dissolved in the upper water layer. It binds very well with metals and you need to not use any metal utensils while preparing it or take at the same time you might be taking trace metals as supplements. I gave it to my horse for awhile. It was supposed to ease their stomach irritability. You also have to be careful about the source of bentonite clay - some are heavily contaminated with lead.