New Research on Sleep Medications in Women

Jun 29, 2021 | Dona Locke | @DrDonaLocke | Comments (55)

Why Sleep?

In the HABIT program, one of our topics is addressing sleep quality because of the importance of quality sleep on daily cognitive function. We discuss identifying sleep disorders, such as sleep apnea (you can see our posts here and here about addressing sleep apnea and adjusting to CPAP therapy). But one of the biggest issues is really sleep disturbance (e.g., trouble staying asleep) rather than a medical sleep disorder. It is common for medical providers to provide prescription medication to help with sleep disturbances, which have been shown to have short-term sleep benefits. However, some patients end up on sleep medications on more of a long term basis. There is new research suggesting that sleep medications may not be as effective in the long term.

The Research:

The Study of Women's Health Across the Nation (SWAN) is a long-term cohort study of a diverse sample women living in the USA. From this sample, the researchers compared the self-rated sleep quality of middle aged women who started a prescription sleep medication to that of another group of middle aged women who did not start a sleep medication. At the start of the study, each group reported similar sleep ratings. After 1 year and 2 years the sleep ratings for medication users were not improved and remained similar to the non-medication group.  You can read the full study here if you wish. In this news release on the research, a Neurologist working in a Sleep Disorders Center was quoted, "The problem with using medication to control insomnia symptoms is it provides patients with some relief but the sleep they get on medication is more sedation than sleep."

The Conclusions:

With these results suggesting the lack of long term benefit of prescription sleep medications on sleep quality in middle aged women and the fact that these medications can have side effects (cognitive being one class of side effects), we'd encourage you to discuss your sleep prescription use with your physician to see if you have other options. We've discussed healthy sleep HABITs in this blog before and that may be a start, but habits for healthy sleep can take some time to develop if there is significant insomnia present. Cognitive-behavioral therapy for insomnia (CBT-i) with a trained provider may be an important part of a sleep treatment plan with your physician. To search for a provider, one option is Psychology Today, an online resource with detailed listings for professionals in the US.

We hope this might stimulate a discussion with your physician about sleep and sleep medications and get you on your way to better quality sleep--for your brain health, your emotional health, and your physical health!

Interested in more newsfeed posts like this? Go to the Mild Cognitive Impairment (MCI) blog.

@nancyguy

Congratulations! It is wonderful how you have put your life together! God's blessings!

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Thats wonderful...you ..just made the most of your situation, I always think of others who are dealing with more serious issues and feel grateful.

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@bobklein

I am a 79 year old man. I have used melatonin for many years, first 2 mg, now 10 mg. My cardiologist insists that I take one baby aspirin each night. I do. However a couple of years ago, Vicks came out with an over-the-counter product ZZZQuil Ultra (25 mg). I take one a night one hour before bedtime. I stopped coffee completely more than 25 years ago. Being from the South originally, I used to love Vanilla Creme soda. I stopped drinking that, and now, I only get up once a night and then go back to a sound sleep. I used to drink a lot of acohol, I try to drink several glasses of filtered water during the day. I go to sleep every night at 11:00 PM. I usually have pleasant dreams, but occasionally bad dreams (like I'm falling). But I wake up every morning refreshed at 8:00 AM. One other thing I do is say "The Lord's Prayer" in bed before I fall asleep and then I pray for my four adult children and my four grandchildren that the Good Lord keep them safe and well and keep them in the Palms of His Almighty Hands. It seems to work for me. Love, Bob Klein

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Nice.

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@justasiam

I am 61 years old and can count on 1 hand the number of nights that I have slept all night and felt refreshed the next day. I have tried everything out there. Melatonin does nothing. Prescribed drugs either don't work at all or give me horrific nightmares! I have tried calming herbal teas, OTC medicine, yoga for sleep, calming sleep apps, black out curtains, did a sleep study (which resulted in no sleep apnea but no other answers either), a sleep schedule, eating protein before I go to bed or later in the night. Nothing works and my brain never shuts up. When I was in college, I would lay awake and write my papers in my head. Having hypothyroidism, celiac disease, great stress and anxiety ( I am a special education teacher and caregiver for my husband) does not help. I have learned that praying myself to sleep is the only thing that works. Not sleeping is frustrating and then I feel sluggish and get migraines!
Good luck to y'all!

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Have u tried cbd with delta8?
One candy puts me to sleep for the night.
I dont have anyone to advise me so i am figuring it out on my own.

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@siosal

Have u tried cbd with delta8?
One candy puts me to sleep for the night.
I dont have anyone to advise me so i am figuring it out on my own.

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My doctor recommended cbd oil. I tried it and it relaxed me but not asleep. What is delta8?

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@bobklein

I am a 79 year old man. I have used melatonin for many years, first 2 mg, now 10 mg. My cardiologist insists that I take one baby aspirin each night. I do. However a couple of years ago, Vicks came out with an over-the-counter product ZZZQuil Ultra (25 mg). I take one a night one hour before bedtime. I stopped coffee completely more than 25 years ago. Being from the South originally, I used to love Vanilla Creme soda. I stopped drinking that, and now, I only get up once a night and then go back to a sound sleep. I used to drink a lot of acohol, I try to drink several glasses of filtered water during the day. I go to sleep every night at 11:00 PM. I usually have pleasant dreams, but occasionally bad dreams (like I'm falling). But I wake up every morning refreshed at 8:00 AM. One other thing I do is say "The Lord's Prayer" in bed before I fall asleep and then I pray for my four adult children and my four grandchildren that the Good Lord keep them safe and well and keep them in the Palms of His Almighty Hands. It seems to work for me. Love, Bob Klein

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Thanks for recognizing my contribution. Sincerest regards, Bob Klein

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I have trouble falling asleep for years., tried Melatonin, did not do anything, got prescription medication, still awake until 2 or 3 in the morning. It is all because my brain will not shut off. Wished there was a button I could turn off. I am not worrying about anything, live a healthy life. I go to bed at 10.30 pm and read a bit, than try to sleep, 3 or 4 hours later I may doze off. In the morning I have trouble getting up because I feel tired. At night my brain goes all over the place,nice memories of the past, current interesting things, my childhood, workplace, holidays . I try to relax and meditate. Etc.Anyone else experiences this ? How to stop my brain working at night and sleep without medication. Margreet.

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@justasiam

My doctor recommended cbd oil. I tried it and it relaxed me but not asleep. What is delta8?

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Its a component if cbd i am not terribly knowledgable about it yet but have found it relaxing and very conducive to a long nights sleep.
I think i may have found it online at either diamond cbd or cbd mall. Its expensive but is sizeable.
Half a gummy is good.
Wish i could tell you more but i just started with it.

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@siosal

Its a component if cbd i am not terribly knowledgable about it yet but have found it relaxing and very conducive to a long nights sleep.
I think i may have found it online at either diamond cbd or cbd mall. Its expensive but is sizeable.
Half a gummy is good.
Wish i could tell you more but i just started with it.

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Thank you!

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@margreet

I have trouble falling asleep for years., tried Melatonin, did not do anything, got prescription medication, still awake until 2 or 3 in the morning. It is all because my brain will not shut off. Wished there was a button I could turn off. I am not worrying about anything, live a healthy life. I go to bed at 10.30 pm and read a bit, than try to sleep, 3 or 4 hours later I may doze off. In the morning I have trouble getting up because I feel tired. At night my brain goes all over the place,nice memories of the past, current interesting things, my childhood, workplace, holidays . I try to relax and meditate. Etc.Anyone else experiences this ? How to stop my brain working at night and sleep without medication. Margreet.

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Margreet that's where I was. I couldn't train my brain off. I tried all of the tricks. Getting up, sitting in a chair and reading until I was really tired, meditation (that always worked for me before), keeping my eyes open in the dark until they closed on their on. melatonin. Stopping the melatonin. Finally I decided no naps during the day no matter how tired I was, drinking plain sleepy time time tea from the super market (a counselor gave me this tip) before I retired, and trying to go to bed at the same general time at night. By 9:00 I was wiped and it finally helped. Naturally since my sleep rhythm was so off I woke early (too early) but I began to regain a bit, a 1/2 hour, then an hour, sometimes only 15 min. But now I'm almost back to normal. Last night I slept 7 hours. Believe me I feel your pain. I'm still waking early between 4:30 and 5:00, but I feel better overall with this added sleep time. Now I can watch a TV show until 10:00 or even 11:00 sometimes. Often I can't. But it was so important to find a way back.We require sleep.

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@lizzier

Margreet that's where I was. I couldn't train my brain off. I tried all of the tricks. Getting up, sitting in a chair and reading until I was really tired, meditation (that always worked for me before), keeping my eyes open in the dark until they closed on their on. melatonin. Stopping the melatonin. Finally I decided no naps during the day no matter how tired I was, drinking plain sleepy time time tea from the super market (a counselor gave me this tip) before I retired, and trying to go to bed at the same general time at night. By 9:00 I was wiped and it finally helped. Naturally since my sleep rhythm was so off I woke early (too early) but I began to regain a bit, a 1/2 hour, then an hour, sometimes only 15 min. But now I'm almost back to normal. Last night I slept 7 hours. Believe me I feel your pain. I'm still waking early between 4:30 and 5:00, but I feel better overall with this added sleep time. Now I can watch a TV show until 10:00 or even 11:00 sometimes. Often I can't. But it was so important to find a way back.We require sleep.

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I'm glad to see your progress. I can go to sleep fine, just not stay. But I do agree about stopping/limiting daytime naps.
I also REQUIRE a good amount of physical activity to sleep - even if I don't feel like it.
Sue

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