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Hives at night: Alpha-gal syndrome?

Skin Health | Last Active: Sep 5 3:19pm | Replies (36)
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@sunshine24

Hi @ryniceal. I'm glad I bumped into this forum. this forum was back in Dec 2018. Everything you described in your post is exactly what I am experiencing right now. I am having hives for about 7 weeks now that only attacks at night then gone when I wake up in the morning.
So that's why I can still go to work & do my normal thing everyday. But at night itching starts at 9 til midnight. I have been to 2 dermatologist both of them said it could be post Covid effect. I had Covid last week of March. Both of them gave me prescription of antihistamine. I tried Benadryl, Claritin, Allegra & now Zyrtex. Been taking Zyrtex for 4 weeks now. After the 2 dermatologist I also seen my primary doctor. I Had blood work at my primary doctor office & the result came good.
It's been 7 weeks I am now feeling scared that this could be more serious issue. I am going to call my dermatologist & will request for skin test or blood work so to find out what could be the reason behind my hives attack at night?

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Replies to "Hi @ryniceal. I'm glad I bumped into this forum. this forum was back in Dec 2018...."
Ginger, Volunteer Mentor | @gingerw | Jun 7, 2021

@sunshine24 Welcome to Mayo Clinic Connect! We are not medical professionals, but we do share our experiences and stories to support others along their journeys.

A few things I have tried when my skin itches like that: Is your skin dry and needs a lotion? Or a new lotion? Have you looked at your detergent used for laundry, or the fabric makeup of the sheets on your bed? It it too warm in your bedroom, or under the covers? It might be something as simple as tweaking one of these variables.

Please let me know if any of this rings a bell to you?
Ginger

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axtc | @axtc | Feb 5 2:26am

Hey. Your story is exactly like mine. I was told my chronic hives were a result of getting covid back in 2021. I’ve seen allergists, dermatologists, naturopaths, etc., all who never really have answers on why it only ever really acts up at night. I have to take antihistamines everyday to prevent the flare ups/resolve them whenever I wake up in the middle of the night. It’s been a couple of years since your post - have you ever figured out what the cause of it was? I know I don’t have Alpha-gal syndrome - I’ve been vegetarian for the past decade now.

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