COVID vaccines and neuropathy

Posted by cue @cue, Feb 15, 2021

I am 85 with small fiber neuropathy that is getting worse. My neurologist thought it would be a good idea for me to wait with the covid vaccine and not be first in line to see how it affected other people with neuropathy. Probably because it is a new technology. Has anyone had a problem with neuropathy after receiving the vaccine? If so, which vaccine?

Interested in more discussions like this? Go to the Neuropathy Support Group.

@johnbishop

Hello @sandiaschild, Welcome to Mayo Clinic Connect. I'm sorry to hear of your adverse reactions to the Moderna vaccine. I know you are not alone. A lot of members have reported adverse side effects. Hoping it's only temporary. I suspect doctors can only give an educated guess based on the patients condition and the benefits of the vaccine vs the risks of getting COVID-19.

Have you reported the side effects using VAERS or V-Safe?
-- https://vaers.hhs.gov/
-- https://www.cdc.gov/coronavirus/2019-ncov/vaccines/safety/vsafe.html

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Many thanks for your messages, John. I will report the side effects there and look forward to reading the article. Be well, S

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@amy11

I would think most if not all of the people on this particular site who are reporting adverse side effects from the vaccine have pre-existing conditions such as neuropathy or autoimmune conditions. It might be informative to know what the percentage is of these people who are reporting adverse neuropathy symptoms after the covid vaccine, not just the percentage of the entire population who has been vaccinated. I'm sure it is higher than .01%.

Also risk vs benefit, using numbers only, can get a bit complicated to assess. Not everyone who doesn't take a vaccine is going to automatically get covid.

Not bringing statistics into the mix, I do agree returning to a normal life would be a huge benefit. But there are risks for us with pre-existing conditions that have to be weighed.

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Amy you are correct that not everyone necessarily gets Covid, but those of us with underlying conditions are 3-5 times more likely to get a severe case than the general public, which increases our risk of aftereffects as well.
Certainly each person must make their own decision, but in order to be around other people, even vaccinated people, the safest choice is to be vaccinated. Otherwise, it seems to me, one who is at risk must continue to live in isolation until the rest of the world gets vaccinated...not a choice I am willing to make.
Sue

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@sueinmn

I think we need to keep some perspective here, and realize in general only people with a problem come looking for answers on this forum. That means we do not know the experience of all PN patients - only those seeking support or information on Mayo Connect.

Also, it is important to know that those who get Covid, especially a severe case, are very likely to suffer aftereffects for months. Neuropathy is among those symptoms, even in people without prior history. Here is just one recent article, https://www.medpagetoday.com/meetingcoverage/aapm/92270

Here is another, written in March 2021 reporting new onset of neuropathy upon vaccination, resolved after a few weeks: https://onlinelibrary.wiley.com/doi/epdf/10.1002/mus.27251
John (@johnbishop) posted several others yesterday here https://connect.mayoclinic.org/comment/597475/

We each must make our own decisions, but if the incidence of long-lasting neuropathy or inflammatory flares after vaccination were common or widespread, I'm sure we would be seeing it in the news, and would be able to find many reports on the Internet. Look at the uproar caused by a handful of confirmed cases of blood clots after the administration of hundreds of thousands of J&J injections.

Finally, neuropathy after vaccine injections is not a new issue - VAERS has reports dating back to 2007 on neuropathy symptoms after injection. So today I took a dive into the VAERS reports to date on Covid vaccines specifically (86080 adverse reaction reports as of April 16th) Most reports of tingling or numbness (maybe 1% of reports) occurred within minutes of injection, with a few 36-48 hours post-injection (I looked at over 2000 records and found only 5) - I guess someone is going to need to some more digging to try to identify people who don't report - either themselves or through the health care system - to figure out how prevalent & how severe the reactions were.
Sue

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How many believe the news in todays world? I don't! I won't take that vaccine, and now they say that anyone who gets vaccinated sheds or transmits that unvaccinated people who get near them can get it. Why isn't the news telling others about this?

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@dablues

How many believe the news in todays world? I don't! I won't take that vaccine, and now they say that anyone who gets vaccinated sheds or transmits that unvaccinated people who get near them can get it. Why isn't the news telling others about this?

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@dablues- Wow, I'm sorry that you feel this way. Connect tries to give the latest trusted, science-based information that people come here to read and learn about. Are you asking if vaccinated people can still get and transmit Covid? The answer, which has been given many times is yes. Vaccines provide an opportunity to slow transmissions so that the pandemic can be controlled. But this only can happen if you are fully vaccinated. The distinction is important because many people do not realize that vaccines primarily prevent the disease but not necessarily infection.

The primary reason for having a full course of a vaccine is reducing the transmission in the population. To stop the pandemic you have to lower the rate of transmission among large numbers of people and the way to get to that is by vaccinations. There is never a 100% guarantee that all people will be fully protected if they are vaccinated. And the odds of catching the disease do not reduce to zero. But by having the vaccine we protect ourselves and in turn protect our community from its spread. Presently, due to the number of people getting vaccinated the number of people getting Covid and the number of deaths is declining.

If you are adamant about not having the vaccine then please take care to wear a mask, wash your hands, stay a good 6' from everyone who you do not know. You will most likely need to do this for a very, very long time. Fully vaccinated people can mingle in small groups with other fully vaccinated people, not wear masks outside if there is not a crowd. In other words, become more sociable again and help open up the country.

Also, vaccinations reduce the severity of the virus. They have not, by themselves, caused anyone to die. If you chose not to be fully vaccinated (2 doses) then you can spread the disease more easily, taking the chance of killing others, including your family members, and helping to spread variants that are much more lethal and spread much more quickly. You will also be someone who helps prolong this pandemic and perhaps facilitate a much longer period of time that people die and infect each other.

I hope that you will watch Mayo's Dr. Poland's podcasts that fully explain all about the virus, how it spreads and how it can be controlled. He is a top virologist and helps make scientific decisions about vaccines around the world. We are very lucky to have him.

This is his latest podcast: https://connect.mayoclinic.org/blog/podcasts/newsfeed-post/covid-19-vaccine-confidence-and-the-importance-of-that-second-dose/

I really do hope that you will reconsider your decision on the vaccines. Sometimes the news can get confusing and depending on your news sources there can be misinformation. Rest assured that Connect and Mayo Clinic would not be advocating the vaccines if they weren't extremely successful. Connect is all about helping people get healthier and trying to manage or prevent illnesses. We believe that being vaccinated against COVID-19 reduces the odds of getting the virus and spreading it. It does kill people and we don't want that.

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@merpreb

@dablues- Wow, I'm sorry that you feel this way. Connect tries to give the latest trusted, science-based information that people come here to read and learn about. Are you asking if vaccinated people can still get and transmit Covid? The answer, which has been given many times is yes. Vaccines provide an opportunity to slow transmissions so that the pandemic can be controlled. But this only can happen if you are fully vaccinated. The distinction is important because many people do not realize that vaccines primarily prevent the disease but not necessarily infection.

The primary reason for having a full course of a vaccine is reducing the transmission in the population. To stop the pandemic you have to lower the rate of transmission among large numbers of people and the way to get to that is by vaccinations. There is never a 100% guarantee that all people will be fully protected if they are vaccinated. And the odds of catching the disease do not reduce to zero. But by having the vaccine we protect ourselves and in turn protect our community from its spread. Presently, due to the number of people getting vaccinated the number of people getting Covid and the number of deaths is declining.

If you are adamant about not having the vaccine then please take care to wear a mask, wash your hands, stay a good 6' from everyone who you do not know. You will most likely need to do this for a very, very long time. Fully vaccinated people can mingle in small groups with other fully vaccinated people, not wear masks outside if there is not a crowd. In other words, become more sociable again and help open up the country.

Also, vaccinations reduce the severity of the virus. They have not, by themselves, caused anyone to die. If you chose not to be fully vaccinated (2 doses) then you can spread the disease more easily, taking the chance of killing others, including your family members, and helping to spread variants that are much more lethal and spread much more quickly. You will also be someone who helps prolong this pandemic and perhaps facilitate a much longer period of time that people die and infect each other.

I hope that you will watch Mayo's Dr. Poland's podcasts that fully explain all about the virus, how it spreads and how it can be controlled. He is a top virologist and helps make scientific decisions about vaccines around the world. We are very lucky to have him.

This is his latest podcast: https://connect.mayoclinic.org/blog/podcasts/newsfeed-post/covid-19-vaccine-confidence-and-the-importance-of-that-second-dose/

I really do hope that you will reconsider your decision on the vaccines. Sometimes the news can get confusing and depending on your news sources there can be misinformation. Rest assured that Connect and Mayo Clinic would not be advocating the vaccines if they weren't extremely successful. Connect is all about helping people get healthier and trying to manage or prevent illnesses. We believe that being vaccinated against COVID-19 reduces the odds of getting the virus and spreading it. It does kill people and we don't want that.

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@dablues

How many believe the news in todays world? I don't! I won't take that vaccine, and now they say that anyone who gets vaccinated sheds or transmits that unvaccinated people who get near them can get it. Why isn't the news telling others about this?

Jump to this post

@dablues In answer to your query about vaccination shedding for the Covid Vaccine. The live virus isn’t used for the serum. So there is no possibility of shedding the vaccine from a vaccinated person to an unvaccinated person. Sadly, it’s another myth that is very damaging to getting the virus under control so that our planet can return to some normalcy.
Here’s an excerpt from a Fact Check article by Reuters in an interview with the Center for Disease Control (the news) explaining why this is not possible. (The full article link is posted below the excerpt)
~~~~~
“There is no way for a COVID-19 vaccinated person to “shed vaccine,” the Centers for Disease Control’s COVID-19 Clinical Team said in an email responding to Reuters questions.
“COVID-19 vaccines give instructions to teach our cells how to make a protein—or even just a piece of a protein—that triggers an immune response inside our bodies. After the protein piece is made, the cell breaks down the instructions and gets rid of them. The immune response, which produces antibodies, is what protects us from getting infected if the real virus enters our bodies.”
The team also stated the vaccines cannot cause people to shed the COVID-19 virus, echoing all the other experts Reuters spoke to, saying “COVID-19 vaccines do not use the live virus that causes COVID-19 and cannot cause COVID-19. Therefore, people who receive a COVID-19 vaccine cannot shed the virus or the vaccine.”
Many of the false posts attribute the “shedding” of vaccines to a “spike protein” in an apparent misunderstanding of how the vaccines work.
The mRNA vaccines “contain only instructions for making spike protein and are incapable of generating virus particles, so nothing can be shed,” said Dr Daniel Kuritzkes, chief of the infectious diseases division at Brigham and Women’s Hospital, one of the world’s top teaching hospitals and part of Harvard Medical School, in a statement emailed to Reuters.
Likewise, the Johnson & Johnson (also referred to as Janssen) vaccine “is based on a replication-defective adenovirus, which means the adenovirus is incapable of reproducing,” he added.
As Reuters explained here the Pfizer-BioNTech and Moderna COVID-19 vaccines use a chemical messenger, or mRNA, to tell people’s cells to make “make proteins that mimic the outer surface of SARS-CoV-2 (the virus that causes COVID-19)…without replicating like the actual virus.” Meanwhile, the J&J vaccine uses a “weakened version of a harmless adenovirus to deliver instructions to cells to make coronavirus spike proteins” that also cannot replicate, as Reuters reported here.

Kuritzkes also pointed out that the mRNA vaccines are degraded within 24 to 48 hours. As explained here, that means they disappear from the shot recipients’ bodies within a day or two. Similarly, the J&J vaccine “gets taken up into cells where it is injected, makes spike protein, and is degraded. It cannot disseminate to other tissues or be shed,” Kuritzkes said.

https://www.reuters.com/article/factcheck-covid19vaccine-reproductivepro-idUSL1N2MG256
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@amy11

I would think most if not all of the people on this particular site who are reporting adverse side effects from the vaccine have pre-existing conditions such as neuropathy or autoimmune conditions. It might be informative to know what the percentage is of these people who are reporting adverse neuropathy symptoms after the covid vaccine, not just the percentage of the entire population who has been vaccinated. I'm sure it is higher than .01%.

Also risk vs benefit, using numbers only, can get a bit complicated to assess. Not everyone who doesn't take a vaccine is going to automatically get covid.

Not bringing statistics into the mix, I do agree returning to a normal life would be a huge benefit. But there are risks for us with pre-existing conditions that have to be weighed.

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@amy11 I agree. Each person has to decide what is best for them. For a person who is at high risk for getting the covid virus then perhaps the risks from the vaccine may be better. But for me who has a very low exposure risk, I would not want the chance to endure the flare ups. Don’t forget we have no information on how long the protection from the vaccine will last. Are flare ups possible again from the boosters? We do have a lot to consider when making a decision. It is difficult because not much is known about the short or long term effects of the vaccines in our bodies. This is an emergency vaccine. Not enough time was used to find information. Normally it takes years not months. Everyone who receives the vaccine agrees to be an experimental subject. No one can be held responsible for what ever happens and there is no going back. We make the best decision we can based on facts. We are still learning about the effects of the virus as well.

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Reuters, Snopes and all those fact checking sites are left wing hacks and you don't get the truth. You need to do your research, align yourself with others who have researched, listen to other doctors and nurses who have stated the vaccine is not safe. Anyone who want to believe this is a safe shot, and that all it is, is a shot. Not approved. Show documents that prove it is safe, and that it is APPROVED as a Vaccine and not just approved for emergency use. You or anyone that wants to put an experimental drug in your body that is fine, but those of us that choose NOT to have any experimental drugs in our body it is our choice. Plus the ingredients and what is explained how this works is not good! This is my opinion and those that other opinions that is fine, since we are supposed to have free speech and able to debate about subjects. The main stream media is not telling the truth, and anyone who follows google, or snopes, or retuers follow the money to see where these companies started and who is actually running them. I will not take any more vaccines since the last one made me sick for 4 months. I should have researched it before taking it but didn't. My mistake. So why would I ever put a experimental drug in my body? Common sense would tell you that is not the way to go. So everyone do what you think is right for you and those that don't want it, don't take it and don't let anyone shame you into it.

Editor's Note:
From the Community Director
For reliable and current, science-based evidence about COVID infection, COVID prevention guidelines, COVID vaccination and treatment of infection, as well as managing post-COVID recovery, please refer to the trusted Mayo Clinic sources:

- Mayo Clinic COVID-19 information: https://www.mayoclinic.org/coronavirus-covid-19
- Mayo Clinic News Network: COVID-19 https://newsnetwork.mayoclinic.org/category/covid-19/
- Weekly podcasts with Dr. Gregory Poland posted every Tuesday: https://connect.mayoclinic.org/blog/podcasts/
- Post COVID Recovery https://connect.mayoclinic.org/blog/post-covid-recovery/

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I'm not debating this anymore with anyone. I know what I'm talking about and trust what I am saying. I don't wear a mask, haven't worn one in a year and am not falling into the fear factor. Has anyone actually researched what has been going on for the past 14 months? If so, then follow what you think is right. I'm done with this conversation since we can go back and forth on this all night long and BTW I love Mayo Clinic, but sorry this Covid Shot is not a VACCINE no matter how you put it. As I said, it is an Experimental Drug that was given the approval for Emergency Use, and am sure you can find that out there if you research it.

Editor's Note:
Mayo Clinic strongly recommends that you receive a COVID-19 vaccine when it's available to you. Mayo Clinic also recommends continued safety measures to slow the spread of the virus, such as:
- Wear a mask when in public
- Wash hand frequently
- Keep a physical distance of 6 feet

Get answers and facts to commonly asked questions about the COVID-19 vaccine https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-vaccine/art-20484859
Read more about safety precautions at Mayo Clinic. https://www.mayoclinic.org/covid-19

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@avmcbellar

@amy11 I agree. Each person has to decide what is best for them. For a person who is at high risk for getting the covid virus then perhaps the risks from the vaccine may be better. But for me who has a very low exposure risk, I would not want the chance to endure the flare ups. Don’t forget we have no information on how long the protection from the vaccine will last. Are flare ups possible again from the boosters? We do have a lot to consider when making a decision. It is difficult because not much is known about the short or long term effects of the vaccines in our bodies. This is an emergency vaccine. Not enough time was used to find information. Normally it takes years not months. Everyone who receives the vaccine agrees to be an experimental subject. No one can be held responsible for what ever happens and there is no going back. We make the best decision we can based on facts. We are still learning about the effects of the virus as well.

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@avmcbellar- You are correct, these vaccinations were all approved on an emergency basis to help stop the number of deaths caused by this deadly virus, and more of its variants. You might be very lucky and not get covid, but that's what it will be luck!. You also could be someone who gets COVID without any symptoms, but yet passes it on to others. You have chosen to take this route.

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