Tips on minimizing withdrawal symptoms from Effexor (aka Venlafaxine)
I have been taking Effexor/Venlafaxine for years and tried to get off it a few times but each time I try to give up the chemical withdrawal symptoms are a horror story and I give up giving up. Anyone got any tips or tried and tested strategies? Thank you
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I haven't been on the effexor very long, may 4 weeks steady
I was trying to evaluate my symptoms if it had increased my anxeity. I have resumed taking the effexor for the past 3 days. Sometines I don't like how it makes me feel. I also under went full gadtric bypass 21 years ago., and i am unable to absorb and metabolize meds normally . feel like im floundering, as i,am having trouble getting into behavioral med clinics etc to monitor and or evaluate for a different antidepressant. Thank you for reaching out
I also have five dreams not sleeping well. Fast heart rate awakens me as well. I am able to slow it down by deep breathing but that feeling is terrifying
@kchastain, you mention that you are having trouble getting into a behavioral medicine clinic to help evaluate your medications and situation. May I ask when are the barriers you're facing? Are you able to speak with the doctor who prescribed Effexor for you? It sounds like you have questions that need to be answered by a medical professional.
I’m off Effexor one month today. It’s hell, u r right. I’m no better. There’s no sun in sight. My problem is I can’t go on anything else right now for complicated reasons do there’s nothing to help me. I know everyone is different but I have to get I. A plane in 5 weeks and there’s nothing to convince me that I can. Itching all over, feet burning and itching. Headaches 24/7. Brain zaps. Pain everywhere. No sleep. Any advice for living in hell?
Can you take the medication for dizziness? Does an antihistamine help? Or a benzodiazepine? My heart is going out to you.
Wow, I have to say that this thread is fantastic. I've been looking through many of the posts since I found the site last week. Thanks to all who have contributed.
A switch in insurance prompted me to get off of Effexor, which I had been on for four years but didn't like as much as Lexapro, which I had been taking previously (switched to Effexor because Lexapro lost effectiveness for me). I've been taking Buproprion now for three months while at the same time weaning off of 225mg of Effexor. My Dr. had me on a taper that took me down to 150mg for three weeks and then 75mg for three weeks and then completely off. I had noticeable symptoms for a few days at each stage but nothing I couldn't handle...until the day after I stopped the Effexor completely. Terrible nausea, dizziness and sweating that day so I contacted my doctor to ask if he saw any issue with splitting the 75mg capsule and going down to 37.5 mg per day. He agreed with that approach so that's what I did for about four weeks with good results.
Last week I decided I needed to take another step so I further split the 75mg capsule down to approx. 18.75mg daily (eyeballing it so obviously not precise). That reduction has been rough. I felt terrible the first day and my stomach continues to be unsettled, especially in the morning. My plan moving forward is to stay at this dosage (18.75mg/day) until I feel better and then reduce again. I have 20+ of the 75mg capsules left so they should last me for quite awhile since I'm only taking 1 every four days. Does that seem like a reasonable approach? I'm concerned about getting stuck at a stage and prolonging the withdrawal symptoms longer than necessary.
is EFFEXOR AN Opiate? Of course, that’s not my understanding. But......
@jeremym - Welcome to Mayo Clinic Connect. Took Effexor for several years but I did withdraw very, very slowly giving my brain time to readjust with the guidance of my PCP. I encourage you to do so! It can be very dangerous for you to speed this process up.
@gamesjr- I hope that this helps:
Medicines like Effexor are called selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It works by increasing and regulating the levels of two different neurotransmitters — norepinephrine and serotonin — in the brain. They treat depressions and sometimes other things. But they aren't opiates, even if both need a withdrawal program. And Effexor is used to help with opiate withdrawal. These drugs have been a major breakthrough in treating depression. An SNRI works by elevating a person’s mood by preventing the reuptake of “feel good” neurotransmitters like serotonin and norepinephrine in the brain, but unlike opiates getting high isn't a side effect.
One drawback of stopping it cold is toy will likely experience what is called SSRI discontinuation syndrome, which mimics withdrawal symptoms. These can occur when a person abruptly stops taking the drug, decreases the dose too rapidly, or even after skipping an individual dose (if their dosage is high enough). In addition to these physical effects, withdrawal from venlafaxine in those who are misusing it may result in unwanted psychological effects as well. These include nausea, depression, suicidal thoughts, disorientation, panic attacks, and confused thinking.
Opiates are a different breed of animal.
no, we care. Thank you and God Bless you.
I was on Effexor for six years when my primary care physician asked me if I wanted to get off this medication. Although I was very thankful for having had the relief from my anxiety during that time, I felt I was ready to try and stop taking venlafaxine. I had been taking 75 mg twice a day and he changed that to 37.5mg twice a day. I did this for about seven months when there was an unexpected supply interruption and I ran out of medication for ten days. I took this as a sign and decided that this was the stopping point. It has been two months and I have had no significant side effects. One observation I have made is that I am experiencing occasional ‘melancholy’ where I reminisce about people, places and things: especially deceased family and friends, “the good ole days”, sort of reaching out to try and grab onto the past. It usually passes quickly (a minute or less) but is pretty emotional in the moment - sadness. Nothing more serious than that and I cannot say for certain that it has anything to do with cessation of the drug. However, I thought it might be helpful (if only for me) to share this experience. Thank you!