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As promised, my successful tapering off Effexor (Venlafaxine)
Below you will find the tapering plan that I used to successfully wean myself off Effexor (Venlafaxine). Feel free to share this with your doctor If you would like. I researched and came up with this plan, which was approved by my doctor, although she thought I could probably have weaned myself off sooner. But the reality is that we all have differing tolerance levels for tapering and weaning off this powerful drug from our bodies. Some people can taper faster, but usually not those who have been on this drug for years (like myself, since October 2002). I tapered off EffexorXR 150mg capsules about 5 years ago down to 75mg, and was on that maintenance dosage for a couple of years until I started weaning off the 75mg a year ago in April 2019. As of October, 2029, I’ve been withdrawal symptom free, but I still have occasional periods of anxiety when triggered. But I realize these waves of anxiety will soon pass, and I cope by deep breathing, taking a walk, having a cup of chamomile tea, etc. Cutting my exposure to watching upsetting news has really helped a lot as well. These days I seek things that bring joy and peace in such a turbulent world. Wishing you all a successful weaning off this powerful drug.
Weaning off Venlafaxine XR 75mg (Effexor-(extended release)capsules:
Weaning plan off plan that worked for BSS:
1. Inform your doctor you are tapering down from 75 mg Venlafaxine and ask them to prescribe 37.50 tabs to help with tapering doses (1/2 dosage down from 75 mg Venlafaxine capsules). The tabs are easier to cut into halves and quarter dosages than counting out beads from the capsules.
2. Begin your taper only after you are on a non-withdrawal symptomatic dosage level. If you were having w/d symptoms at 75 mg, you’ll need to go back to the level at which you were symptomless and stay there for 2-3 weeks before deceasing to a slow taper. NOTE: after successfully tapering from 150mg Venlafaxine down to 75mg for a month, I was unable to tolerate a drop cold turkey from a daily dosage of 75mg down to 37.50mg (50%) without having bothersome withdrawal symptoms of dizziness, brain fog, brain zaps, and nausea. So after researching various tapering plans, I came up with a slower tapering schedule my body could tolerate to finish the tapering from 75mg to 37.50mg, and then on to complete the tapering. Your body may even need slower tapering, so adjust according.
3. Week 1-2: Take 75mg caps MWFSu; take 37.50mg tab on alternate days Tu,Th, Sa. At the end of week 2, if you only have relatively mild to no withdrawal symptoms, proceed to week 3. IMPORTANT: If you have intolerable symptoms, adjust to a slower tapering schedule by adding an additional 1/2 tab on the alternate days (or take a total of one and a half 37.50 tabs on alternate days). You’ll then have to tweak the rest of your tapering schedule. If all goes well, proceed with week 3.
4. Week 3-4: Cut a few 37.50 tabs in half with a pill cutter or exacto knife blade to create quarter pieces. Take 37.50mg tab on MWFSu and take 3/4 tab on alternate days Tu, Th, Sa.
5. Week 5-6: Take 3/4 of a tab MWFSu, and take 1/2 tab on alternate days Tu, Th, Sa. If only mild symptoms, proceed to week 5.
6. Week 7-8: Take 1/2 tab on MWFSu; and take 1/4 tab on alternate days Tu, Th, Sa. If no symptoms, continue to week 7.
7. Week 9-10: Take 1/4 tab on MWFSu; and take 1/8 tab (cut 1/4 tabs in half) on alternate days Tu, Th, Sa. *Notice the quartering of doses into crumbs now...very important to keep small dosage tapering to remain withdrawal symptom free.
8. Week 11-12: Take 1/8 tab crumb on MWFSu; take none on alternate days Tu, Th, Sa. *If skipping alternate days produces symptoms, stay on 1/8 tab crumbs for a couple of weeks before alternating skip days for a couple of weeks.
You’ll find that this schedule may have to be tweaked for you by extending the time you stay on a taper...possibly up to 3-4 weeks before beginning a new tapering down. It all depends on how you tolerate the first two weeks.
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Effexor Withdrawal
Here is my story with Effexor. Fifteen years ago I was diagnosed with Depression and was put on Zoloft. Then I was switched over to 150 mg of Effexor for about ten years ago. Five year ago I started a consistent mindful meditation practice and due to a major increase in my overall happiness I started a tapering off process that would take about 3 years. First it was 75mg for about 1-1/2 years and then 35 mg for about the same amount of time. Each time I changed to a lower dosage the symptoms were the same, i.e. nausea, brain zaps and extreme irritability which caused problems at home and at work. The irritability was a major concern each time and I was not sure if the irritability was a withdrawal symptom or just the way things would be for me at this new dosage level. Each time I hung in there only to find myself stabilizing back to myself gradually after about two months.
About five weeks ago I went “cold turkey” off the 35 mg of Effexor. For the first week the symptoms were as mentioned above. I anticipated the irritability knowing what kind of trouble it can produce. It was not that bad since I had been through it before. However at the start of the 2nd week I caused a major fight with my wife over the smallest thing, then I said some pretty nasty things to my neighbor over another small issue and again another fight with my wife at the end of the week. Then I fell into a deep hole of depression, an experience that I would not wish on anyone. The third week I went to a one week silent meditation retreat that I had scheduled earlier in the year. That entire week was awesome. Not one brain zap or irritable feeling the whole time, so I honestly felt like I was out of the woods. After returning home the brain zap started reoccurring as well as some irritability. I guess the meditation was counteracting the biological changes that were occurring within my nervous system. The fourth and fifth week I notice I felt flat emotionally but on a positive note I was now experiencing very few brain zap. Over the last three days joyfulness has started to arise particularly after meditation and exercise which is a state I normally feel quite often. I can’t say for sure yet but I think I am starting to stabilize; only time will tell.
The main purpose that I am trying to convey is that the symptoms in my case were quite horrible and that I was tempted each time I reduced my medication to give up and just accept the fact that I needed to take the mediation for the rest of my life but for some reason I persisted and in the end I am so happy I did. I am not saying this will be the case for you, but for sure I would recommend hanging in there for a while before giving up and to do this while keeping your doctor in the loop. Good Luck!!
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18 Reactions@jeffc16 An amazing journey. Good to hear of a positive experience. I so recall those brain zaps and irritability. I would not want to experience this type of thing again. Enough to steer me clear.
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5 ReactionsEffexor doesn't come in liquid form?
I just read your post again.
You wrote so clearly your plan of tapering.
Thank you for being a great role model.
Many thanks!
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5 ReactionsYour welcome, Ellen. I hope you find the peace you seek from weaning off this addictive drug that carries so many undesirable side effects. Enough is enough.
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10 ReactionsNo, it doesn’t to my knowledge.
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1 ReactionThanks a lot.
I'm on 75mg an 37.50 mg of venlafaxine for 6months how hard will it be for me to come of them. As they have made me much worse. Just want of them would really appreciate any help at all thanks so much
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1 ReactionI tapered from effexor 187.5 mg by my doctor in 4 weeks and my life has been hell. I am 84 years old - a widow for 20 years and have a lot of issues in that time. Years earlier my physician prescribed zoloft. It worked well and 3 was weaned off it by my doctor in a relatively short time without having any problems. I think my doctor prescribed effexor due to my age. What a tragedy this drug has made of my life. Why aren't using your plan. It seems sounder & safer than the plan my doctor used. I no longer want him to treat me. I would love to send him your way of tapering. I will not use your name unless I have your permission. Thanks and God bless.
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7 ReactionsHi there, any updates? How is it going? Thanks 🙂