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Severe stomach pain

Digestive Health | Last Active: Aug 25, 2025 | Replies (425)

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I have had acute abdominal pain since April 2011 and it has escalated over the months.. The pain begins early morning, remains unrelenting and escalates throughout the day. It is sharp at times and gnawing most of the time. It radiates down from my sternum and to the lower left of my abdomen. My family doctor nor GI specialists cannot find the cause. I have had CT scans, ultrasound, video capsule endoscopy, colonoscopy, blood tests, push endoscope, H pylori tests, ova stool test for parasites and MRI, to name a few. EVERY test result has been returned as "unremarkable"--no cause found. I am currently taking Paxil 25mg, Nexium and Oxycodein for the pain. Nothing has helped me determine the source of this pain. I am reaching out to this community to see is anyone has a similar experience.

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Replies to "I have had acute abdominal pain since April 2011 and it has escalated over the months....."

A lot of my pain and true with my test except two breath test saying SIBO ( which many drs say too many false positives) stool test was neg for SIBO only one blood test showed high inflammatory markers so they say IBS . Gut cognitive therapy, no dairy, sourdough bread only ( too many say gluten free products have too many additives) stretching, excersise , tons of water and tried every antidepressant with horrible side effects to help relax the brain to gut .

Iam going thru samething can you help me me ..find answers ..pls..i am pomona ca. Ive been in pain 6 months non stop

I have been suffering for 10+ years from an undiagnosed abdominal pain. My doctors have just told me anxiety. Usally I feel like I'm going to throw up, but never do. Rarely I get a bad headache and stomach ache and then throw up. Recently I have been feeling really lightheaded and weak, either before or after I eat. The only thing that seems to help that is DPT. My abdominal pain can feel like cramps or in the same area, like pinching, sometimes I want to cry(because I am tired of being in pain), and I havn't had solid stools in 2 or so months. There are foods like milkshakes and pineapple that I have stopped eating because everytime I eat/drink them I get very nausues. But one day I will eat oatmeal for breackfast and 3 days later the exact same thing, and I have to go to the nurse at school it hurts so bad. There are no similarities from journaling my feelings. Does anyone know of any gut doctors or what this might be? I don't want to be in pain forever.

No one has been able to help me and I’m at my wits end with the pain. It is daily pain that will not go away with pain relievers.

On January 20th I randomly burst out with hives all over my body, coupled with angioedema of the lips and swelling in my extremities. Soon after came right side abdominal pain, nothing crazy but was uncomfortable. I saw my PC doctor who referred me to an allergist that I have been working with for treatment of the CSU and angioedema. I’ve been on multiple different antihistamine regimens as well as prenisone during severe outbreaks.

My abdominal pain has landed me in the ER four times. I have had 4 CT scans, 3 with IV contrast, 2 X-Rays, bloodwork and everything comes back clean. No organ concerns and no elevated/abnormal lab levels. The only findings were minimal fatty liver, and enlarged spleen (14.5cm). My last CT finding finally showed diverticulosis of the sigmoid colon and my spleen was back to normal size.

The pain is diffuse, primarily right side and can be upper below rib cage, middle, lower and near my hip. It radiates to my back occasionally and sometimes is on the left side. The pain can be dull, sharp, throbbing, really depends on the day. It can be debilitating at times.

I have had a colonoscopy/endoscopy and there were no obvious findings during the scopes. I am still awaiting biopsy results that they said could take 8 weeks. The pain went away for about a week and a half after my scopes and now has come back worse than it was before. I don't know what to do anymore.

I had a ruptured brain aneurysm. However I recovered extremely well from this except my CSF fluid was not draining. I had two lumbar punctures which helped however my neurosurgeon advised me that I needed to have a VP shunt put in place. I did not realise at the time that this would involve open abdominal surgery. Ever since I have suffered for over the past five years with chronic severe abdominal pain which progressed over the years to my upper abdomen and intercostal muscles on both the left and right sides. I have have CT, X-ray, endoscopy, colonoscopy, and like yourself the medical consultants have found no cause that they can see. After five years of tortuous pain both day and night, I cannot walk and am basically bed bound. My GP has prescribed various medication such as fentanyl patch, co-codamol, antispasmodics, and other muscle relaxers but the pain remains unabated. The hospital and consultants send me home to "manage my own pain". I admit that I have spent a lot of time contemplating suicide however our innate human behaviour advocates survival and I have two young adult sons who give me the only reason to keep going. I believe that nerve damage/compression was caused during the VP shunt surgery however the Consultant neurosurgeon whose team carried out the operation take no responsibility and in fact now don't even give me normal routine follow up scans as I still have two unruptured brain aneurysms as they just want to distance themselves from me and the damage they caused. I am currently on a waiting list for the last two years to see a pain specialist however it could be another 3-5 years before I get an appointment. Many people with nerve damage are misdiagnosed as having IBS/IBD. I wonder if you could ask your doctor to refer you for tests to ascertain whether it may be nerve damage/compression which is causing your ongoing chronic severe pain. On a more personal note I have complete empathy for your situation and hope that someday someone may be able to help you. Be progressive in seeking referrals and don't wait for a miracle.

I have been going through similar stomach pain for the last 8-10 months, something all the tests so far show nothing. I have have CT, X-ray, endoscopy, colonoscopy, ERCP, HIDA scan, gastric emptying study, you name it I probably have had it. I already had a partial gastrectomy 13 years ago for gastroparesis and have been good up until the last 8-10 months. I have lost 35 lbs and still losing. Doctors seem to be throwing their hands up, even the specialist I am seeing at UPenn which is supposed to be one of the best places for gastro issues. It is appalling how the doctors have no empathy and just want to give you pain meds without trying to figure out the cause. Been looking to this site to see how others have been handling similar issues. Help!

likely is mesenteric panniculitis

I have been going through the same thing for the past 10 months. I was diagnosed with gastroparesis 13 years ago that ended up with a partial gastrectomy and have been doing well until the last 10 months. I have been unable to eat or drink without pain and nausea and have lost 38 pounds.. I have had upper endoscopies, ERCPs, CT Scans, bloodwork and every test you can think of and they are still not sure what is causing the pain, why after so many years has it come back... I am now off to another specialist at Temple that specializes in gastroparesis for a consult. I keep checking this site for new options and hoping to find some new path to bring to the doctors to help address the issue. They are now talking about a feeding tube because I am still losing weight at an alarming rate...