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bosco17 (@bosco17)

John Hopkins Webinar on transplant recipients and vaccines

Transplants | Last Active: 4 minutes ago | Replies (45)

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@rosemarya

@snorris, Thank you for the link to the interview. It is very helpful and has given me the information in clear understandable terms.

Welcome to Connect. I can see that you have ben a member for a while, and that this is your first post. I am glad that you chose to jump in with this information.
Are you a transplant recipient?

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Replies to "@snorris, Thank you for the link to the interview. It is very helpful and has given..."

Hi Rosemary. My husband received his new liver at Mayo Rochester in October 2018. It’s been a long road, 33 days in hospital post transplant, he’s doing well now, and we have found this forum very helpful.

Evidently Tacrolimus is a prophylactic for Covid 19 in preventing sever infection.
Tacrolimus is immunosuppressive by inhibiting calcineurin, and suppressing the early phase of T-cell activation, and the expression of many cytokines (IL-2, IL-4, TNF-α and IFN-γ) that are needed in the activation of the cellular immune response, possibly preventing a cytokine storm as observed in severe COVID-19.Jun 27, 2020
https://www.ncbi.nlm.nih.gov › pmc
Calcineurin inhibitors revisited: A new paradigm for COVID-19? – NCBI – NIH