Sorry to hear your dad experienced the bad reaction again, @devehf. Can you explain why they thought he would have less of a reaction now than before?

@devehf Hello Dave. My name is Nancy and I am one of the Mentors in the Blood Cancers Group. I have taken Revlimid with Velcade and Dexamethazone with a switch to Darzalex in between. My experiences have been varied but in all instances I had side effects that definitely compromised my quality of life. I eventually discontinued it. But not before it took me into remission. The point probably is that everyone is different so we are fortunate research is producing more and more quality and effective treatments. And it sounds like your dad has caring professionals helping him navigate his options. I hope that you will come back and let us know where his journey takes him. Peace, Nancy

Dear Dave,
My mom took Revlimid last year and experienced severe itching on her body. What we did with the nurse was change her pajamas and clothes to natural fibers like cotton and linen instead of synthetic fibers and use Acid Mantle on her skin every day after showering. Whenever she had itching on her legs or ankles, she would apply Acid Mantle, and it was very refreshing, allowing her to sleep peacefully. I decided to buy Bayer's Acid Mantle soap and use it for her daily bath. Also, the Eucerin shower products made her itching almost disappear, allowing her to continue her treatment. I think in our case there was a strong cutaneous component. A few months ago, her treatment was changed to daratumumab, and it has been very beneficial. Tomorrow, she will have X-rays and an MRI to see how her bones are doing. Good luck to everyone! Caregivers and patients.