Vitamin B12 and Neuropathy

Thank you for your response and time. To actually have conversation like this is refreshing. You have answered a question that I have been trying to research. That was if people who hand Central Sensitization Syndrome also had thyroid disease.I have been told that my thyroid disease affects this syndrome indirectly. In my experience that is so untrue. The neurologist agrees with me on this. So now I am even more puzzled. I will give the last example of this. Once a year I have the blood test for this problem. This recent test showed I had to high a level of that med in my system. That happens every so often. My primary doctor decided he would lower that dosage. I was taking 150 mg and he lowered it to 112 mg.It takes about 3 days before that process really takes affect. It was the affect I had a problem with and the subsequent pain it caused me that I paid a price for. I woke up in the morning and my world became a very ugly place. Anger and rage was part of that. I didn’t know what the hell was happening to me. By the time I made it to my neurologist, I had started to calm down. It took about a month before my life became livable again. The doctor and I talked about this for awhile band he was hoping that my body would become adjusted to the new dosage. That sort of happened. My body did a better job at that than did my mind. I found myself at an even high sensitivity level if that is possible. The other problem is I get muscle spasms on an off ever since I detoxed from that Fentynal patch. They happen everywhere and at odd times. Sometimes for no reason at all. Usually they only last for a couple of minutes and no longer than a hour. After that med problem and within that month, the muscle spasm from hell hit me. It went from the middle of my back all the way to my foot on my left side. I was crippled by it. Pain from hell. It wouldn’t stop. I had to make an emergency visit to the neurologist and he used the injection I get for my nerve damaged surgical site, to relieve that situation. Here is where my chemical sensitivity played in and that increased sensitivity blew me out of the water. Up until this point I could take two injections at one time with very little after affects. This time I went straight to hell. It takes about three days after those injections to feel some of the aggravation the steroid causes to the nerve endings. This time it felt like someone just lit me on fire. It took about another week before that to calm down. Now I am more cautious about anything to do with meds. I don’t know where I am at in that situation anymore. I am still in this hypersensitivity state. I will look into your suggestion about this med and thanks again for replying.

@lorirenee1
Hi
Normal B-12 is between 200 & 900. What level does your doctor or nurse recommend it be at.
I know B-12 helps numerous things like nerve & blood cells and helps prevent anemia. It also helps make DNA etc.
I know a man in Canada who is able to control his seizures with B vitamins alone.
Anxiously awaiting to hear what your nurse or doctor has to say about the proper level of B 12 for neuropathy. I may need some too.
Jake

I am sorry but I found it weird. I just spent time doing something that I not use to doing and rarely do. When I am in that thought process, there is no humor. Since you have shed some light on what this was about, no big deal. There is still some sarcasm and humor left in me.

Hey Leonard and Lori Renee
For what it's worth...while going through all the motions to find the underlying cause of my SFN diagnosis, my B12 was found at 219 and methylmelonic acid levels off. My Neuro sent me asap for injections every 2 weeks and retested me every 3 months until B12 reached 535. At that point he was satisfied for me to take oral B12 daily. He will continue to monitor unless I feel the immediate effects of B12 slipping earlier.

@rwinny
Thanks for the information
Jake

Thank you for your response and time. To actually have conversation like this is refreshing. You have answered a question that I have been trying to research. That was if people who hand Central Sensitization Syndrome also had thyroid disease.I have been told that my thyroid disease affects this syndrome indirectly. In my experience that is so untrue. The neurologist agrees with me on this. So now I am even more puzzled. I will give the last example of this. Once a year I have the blood test for this problem. This recent test showed I had to high a level of that med in my system. That happens every so often. My primary doctor decided he would lower that dosage. I was taking 150 mg and he lowered it to 112 mg.It takes about 3 days before that process really takes affect. It was the affect I had a problem with and the subsequent pain it caused me that I paid a price for. I woke up in the morning and my world became a very ugly place. Anger and rage was part of that. I didn’t know what the hell was happening to me. By the time I made it to my neurologist, I had started to calm down. It took about a month before my life became livable again. The doctor and I talked about this for awhile band he was hoping that my body would become adjusted to the new dosage. That sort of happened. My body did a better job at that than did my mind. I found myself at an even high sensitivity level if that is possible. The other problem is I get muscle spasms on an off ever since I detoxed from that Fentynal patch. They happen everywhere and at odd times. Sometimes for no reason at all. Usually they only last for a couple of minutes and no longer than a hour. After that med problem and within that month, the muscle spasm from hell hit me. It went from the middle of my back all the way to my foot on my left side. I was crippled by it. Pain from hell. It wouldn’t stop. I had to make an emergency visit to the neurologist and he used the injection I get for my nerve damaged surgical site, to relieve that situation. Here is where my chemical sensitivity played in and that increased sensitivity blew me out of the water. Up until this point I could take two injections at one time with very little after affects. This time I went straight to hell. It takes about three days after those injections to feel some of the aggravation the steroid causes to the nerve endings. This time it felt like someone just lit me on fire. It took about another week before that to calm down. Now I am more cautious about anything to do with meds. I don’t know where I am at in that situation anymore. I am still in this hypersensitivity state. I will look into your suggestion about this med and thanks again for replying.

I have the same thoughts on this as you. I see a lot of people on this site that are looking for answers and some kind of relief. I have always tried to find solutions to my problems in dealing with life situations and most of the time I have been successful. This problem just has way to many variables to solve. If I was to go about this practically, I would need a team of very experienced doctors, an expert in each field that applied to my medical problems. Then there would have to be a doctor who could talk to these doctors and organize an filter out what was necessary information and what was just not going to be of any use. That doctor would have to spend time listening to me as what symptoms I was experiencing. This alone is even confusing to me. If you look up those medical problems, the same symptoms show up in all of them. You really can’t tell which one is causing what. That is just to weird. There are no real medical tests for what I have, so how would you determine what is going on? In my case, my chemical sensitivity started before I had that surgery. One thing I have realized in my case is what ever was happening before Central Sensitization, has carried over and those medical problems have been hypersensitized. I never really noticed any problems dealing with my thyroid disease. Now I do. The chemical sensitivity has become unreal. Since I have read the replies I have gotten, I see that other people have had their senses affected. Mine are ridiculous. Light, hearing, smells,skin, touching something and even cognitive function are mine. I never experienced anything like that before. Just going to my neurologist office and having someone start talking or reading a newspaper and changing pages, will drive me up a wall. I have to wear sunglasses anytime I go outside and sometimes that doesn’t even work. My eyes start to hurt like hell and I get severe headaches. I never use to get headaches. I have worked outside most of my life. It never bothered me. One things that pisses me off is the lack of personal freedom I use to enjoy. Now I need to depend on my wife just to go somewhere. I don’t drive anymore. Not because I can’t drive but because I can’t go to the DMV to renew my license. Too many people, too much noise. I have tried three times and it causes too much stress just being there. The result of that stress are muscle spasms for three days and they are excruciating. My life now consists of a two a day walk with my dog. I can usually do this for about an hour a walk. Yes my feet hurt but they hurt worse if I just stand still. I find that doing nothing is more painful than doing something. I exercise 7 days a week. I have been doing that all my life anyway and I use to play different sports will going to school. Weight lifting was something I did all the time. I can’t do that anymore. I have found other ways of exercising, like pull-ups to do the same thing. While working for the telephone company, I blew out my knee while climbing a pole. I had to eventually have a joint replacement done. I need to exercise just to be able to maintain that. I will bring up something that has crossed my mind and I have experienced maybe so of you have. If you had a medical problem an need to go to the emergency room, would you? I won’t. They can’t help me for a lot of reasons now. They wouldn’t understand how to go about it and would cause me more problems. Again that is just me and I wouldn’t tell anyone to follow that idea. I am a realist when it comes to my future. While I see other people looking for answers and believing in something will come along to resolve this, I don’t. Too much confusion on just the research end of this medical diagnosis. I am 71 now and the natural aging process will not stand still while these people are doing their thing, and the body just breaks down. All the aches and pains that come with that will do me in. Just the stress that this crap is causing me now, non stop, will do me in. All realities. What I have decided to do is deal with it as long as I can. I have never been into using drugs. I was never an addict before I was made into one by doctors. I don’t plan in going in that direction ever again. I will have to decide at some point in this mess, whether I can tolerate anymore pain. Again this is just me and I have lived a long and very hard life, so I wouldn’t want anyone else to follow what I do or say.