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Anyone Heard of Pirenzepine for Small Fiber Neuropathy?

Neuropathy | Last Active: 23 hours ago | Replies (108)

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@jordanabrams30

Really great points. One of the things Mr Kim mentioned to me was while the focus is on DPN and CPN the science appears to show the mitochondrial make up of most neuropathies appear to be similar. Now the only concern I have is outside elements that caused the neuropathy in the first place will they allow recovery. For example if you have autoimmune which is what it appears I have isn’t addressed will it allow for recovery or will it continue to attack? Just something to consider one thing that is of interest to me would be for them to look at a pill solution to become system wide and not so specific to skin soluble; potentially addressing autonomic nerves etc. At the end of the day it appears someone is making great inroads to something no one else has been able to in the past.

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Replies to "Really great points. One of the things Mr Kim mentioned to me was while the focus..."

Just to say that pirenzepine (PZ) in pill form already exists. I’m in the U.K. and here it is used for hypersalivation (drooling) caused by other medications. Apparently it used to be used for stomach ulcers. It would be worth looking to see if it is available in the US. The scientists at WinSanTor, specifically Paul Fernyhough is conducting preclinical studies to see if PZ induces outgrowth in autonomic nerves.