@ginej I'm not sure if you were asking me or someone else. I took two a day while I was taking the Vancomycin for the 3rd bout. While taking Deficid for my 4th bout, I also took two a day. I now take one Florastor and one other less expensive brand that is 440 mg of S. Boulardii every day. I really prefer it because it survives stomach acid and goes to work in the colon. I've not relapsed since last October. I knock on wood every time I say that. After 4 bouts in 2018, I've never been through anything so debilitating. I will never take Clindamycin again which start this terrible ordeal.