@denisemarys I also did the Vanco taper after my third relapse. Not sure how long you're doing it. I was five or six weeks total and also started taking Florastor as suggested by my GI. After finishing it, I was good for 3 weeks before my 4th relapse. I was then given Dificid for ten days. I finished that on Oct. 26th. I have not had a relapse since finishing the Dificid. It's really expensive and my insurance wouldn't cover it until I had tried others meds. I did Flagyl for 10 days, Vanco for 10 days, Vanco taper and then Deficid. I've never gone through anything like this in my life. And it all started with taking Clindamycin for a sinus infection. I've had three back surgeries and those recoveries were a piece of cake compared to C.diff. I'm happy I found this site where others can share and as you said, "you are not alone." I pray the Vanco taper works for you.