@serenityva C.diff is the most difficult thing I've ever dealt with. I've had 4 bouts of it and have taken Flagyl, 2 rounds of Vancomycin and finally the expensive med Fidaxamicin (Dificid). My first bout was in April and I went for 10 days thinking I had E.coli from romaine lettuce before the test came back positive for C.diff from the Clindamycin I had taken earlier. I finished the last med on Oct. 26th. Two months is the longest I've gone since contracting the dreadful C.diff. I too have disinfected our entire house. Clorox wipes are in all the bathrooms and I've mixed bleach with Simple Green and sprayed down so many things. Hand washing is so important and hand sanitizers do nothing to kill the C.diff spores. You mentioned you and your husband will be alone for Christmas. I was around my family during all 4 bouts of C.diff. None of my family have been infected. To be extra cautious, I never used our guest bathroom while I was sick. And we still wiped it down with Clorox. If your family members are healthy, my doctors said they had nothing to worry about. From everything I've read, our percentages of getting C.diff relapses get higher with every occurrence. So I'm very thankful that I've gone almost two months now without a relapse. I've been faithful taking the probiotic Florastor and hand washing. I will go after the first of the year for a colonoscopy. I'm actually concerned about that after everything I've been through.