Weaning off Effexor with CBD Oil
After having my son last year, I had really bad postpartum. I talked to my doctor and she prescribed me Effexor. I started out with 75mg, it wasn't enough, so the doctor prescribed me 150mg. I was on that for awhile, but the side effects were interfering with my libido, so the doctor suggested I wean off of Effexor and start Wellbutrin. As I was weaning, I had the worst withdrawal symptoms. The symptoms were too much, so I quit trying to wean completely off of the Effexor, and was taking the 75mg of that and 150mg of Wellbutrin. It helped, a little, but my goal was to get completely off of Effexor so I'm trying again. And now my goal is to get off of the Effexor and Wellbutrin completely and try something natural like CBD oil. It's so hard dealing with the withdrawal symptoms, I'm trying to tell myself that this is a temporary thing and it'll be worth it in the end. Any advice for the symptoms? And has anyone had success with CBD oil for helping to wean, and using that for depression and anxiety?
Thanks!
Interested in more discussions like this? Go to the Depression & Anxiety Support Group.
Connect

Some antidepressants make anxiety worse, at least at first. Get a firm diagnosis that rules out a Bipolar spectrum disorder. The drugs treating this kind of depression/anxiety are completely different.
-
Like -
Helpful -
Hug
3 ReactionsHi there, @lindeyt01, I just read about your wish to use CBD to help prevent withdrawal symptoms. I see that you asked for some feedback for those who have done this type of withdrawal and Ginger is just the perfect mentor to help you.
Just one year ago, my PCP and I decided together that I should withdraw from Nortriptyline and replace it with an extra dose of CBD. I use a 2:1 CBD/THC for all of my pain management from Small Fiber Neuropathy (SFN). The withdrawal and replacement with medical cannabis worked but not without some really tough days fighting constipation. So be patient, Evaluate your progress with your clinician. Check-in with @gingerw as you move through the process. At this point, I think I am done with anti-depressants. However, when my neurologist prescribed Nortriptyline it was a lifesaver in many ways,
May you be safe and protected from inner and outer harm,
Chris
-
Like -
Helpful -
Hug
3 ReactionsHi Sheree, Your post was put on in July 2019. I am very keen to see if you were able to come off Effexor using cbd oil.
Hello @kieren09 and welcome to Mayo Clinic Connect. I noticed you started a new discussion with your first post on Weaning off Effexor with CBD Oil and then found this discussion, which is perfect. You will notice that I have removed your first post so you can connect here with members on this topic to get the support you are seeking.
One tip to help you notify members of your interest to connect with them is to include the "@" + their username/handle such as @shelleee in the case of Sheree. Unfortunately, it does look like that member is not receiving email notifications, however.
You will find other helpful members in this discussion such as @artscaping @grandmar and @gingerw who may all provide you with some helpful perspective on this topic.
As we wait for them, can I ask if you have started by consulting with your doctor on this plan to wean off Effexor? If so, what was recommended?
-
Like -
Helpful -
Hug
1 ReactionI suggest getting 10 mg of prozac to ween off Effexor then down to 5 my then get off. Effexor is really rough to come off Prozaccis used often to get off these.
@kieren09
Welcome!
How can I help you regarding weaning off of Effexor?
GRANDMAr (Ronnie)
-
Like -
Helpful -
Hug
1 Reaction@kieren09 @amandajro Welcome to Mayo Clinic Connect. I do not have any experience with Effexor, so cannot offer you any tips or information. I do use CBD tincture or capsules, for help with pain control or depression maintenance. Usually I start at 30 mg and will go up to 60 mg.
Ginger
I’m wondering if anyone has or knows of anyone who has managed to come off Effexor?
-
Like -
Helpful -
Hug
1 ReactionAnd how did they achieve it?
Thank you. Cbd oil will be my next step but I would need to come off Effexor first and I am very sensitive to it and finding the withdrawals unbeatable.