First visit to Mayo and traveling alone: Winter advice?

My initial appointment is with GI clinic. I've been seeing numerous doctors for 8-9 years, had dozens of tests, with no clear diagnoses. Some treatments have made me worse, but recent test results point to possible autoimmune liver. I wondered how it works when one's problem covers several specialities as mine does? I start at GI, but will likely need rheumatology (possible connective tissue disorder), endocrinology (I have Hashimoto's), and even neurology (weakness in legs recently). I booked a hotel at Centerstone Soldier's Field based on advice from my cousin, as I wanted a small kitchen. I am traveling from California and wonder if there is advice on what to expect in the deep of winter--my appt is Jan 24! I've read mostly good but some bad on these blogs regarding visits, and my biggest worry is I still won't get a firm diagnoses after all the time and money traveling! I'm wondering how referrals work, or do they just send you for tests and consult doctor to doctor?

I know some have advised to NOT be alone, but there is no other way I can make the visit. I'm pretty independent, but I dread the trip as I don't feel well much of the time, and it will be dead of winter and a long trip. I am booked to take shuttle from Minneapolis airport to Rochester hotel. Any advice on a first-time visit in winter would be welcome--Ruthie in warm So. California