How did you manage the pain side effects of Prolia?

@sue225 yes my bone density has always improved when taking Prolia. I am grateful for this.

@sue225 I forgot to mention my next injection is in May and I am glad it is also working well for you.

Just had my fourth in January. Next one July.

@migizii I was under the impression that only Forteo and Tymlos, and the newer drug, Evenity? improved bone density. That's interesting to hear that Prolia does also. I purposely chose to go with Tymlos because at my bone density level I need improvement. Starting it has gotten delayed a few times but it looks like it's "a go" tomorrow. I have an appointment with the helper from Tymlos for my first shot. I have to admit, I'm sort of nervous. Not so much about giving myself the shots, but about potential side-effects.

My bone density got substantially worse in the last year despite doing all of the things that are recommended to do naturally. Last year I would have gone on a bone maintenance drug but that got delayed and then the pandemic really put things off so here I am now, a year later.
JK

@contentandwell Hi JK,
I'm looking forward to hearing from you after your first month of treatment to see what side effects if any, you experience with this drug. I hope it works well for you without any effects.

@jk. I was on Tymlos twice for about 4 months at a time but would have to stop due to having increased pain in my legs. I had tried Forteo a number of years ago but that was unsuccessful due to getting migraines. I became very ill from my only Reclast injection. Thus far, IV Boniva worked for awhile and Prolia have been my only successful interventions.I don’t know what the future will hold once I can’t take Prolia any longer, but I am having better DEXA scores. Yes, I also had no success with only natural supports when first diagnosed. I hope you can proceed now with your journey.

Thank you, @migizii I realize of course that all drugs have side-effects for some people but it seems as if all of the drugs for osteoporosis have way more than their share of problems. I hope Tymlos will be OK for me. I am just about to head upstairs for my second shot.

I had to reduce a statin because it caused terrible pains in my legs. I had no idea that was the cause, my husband thought I was exercising too much, but I mentioned to a friend that my legs were killing me and she immediately asked if I was on a statin! Sure enough, that was what caused it. The doctor switched me to a half dose of what I had been taking and it's tolerable now. I did some research and the drug I am on is one that is least apt to cause those problems.

I just really hope I don't have that problem from Tymlos, but time will tell.
JK

I believe you can take Prolia for a long time.

@contentandwell Hi JK. Have you had your first dose of Tymlos?

@hopeful33250 I did my first shot on Thursday under the guidance of a "Clinical Educator" from Tymlos, on Facetime. That went well, my heart rate did not go up, or if it did it was only by a few beats. I tend to have a low heart rate anyway - resting heart rate is about 53 usually. I had a very slight amount of light-headedness for a brief amount of time. I did my second shot last night. I had the same, but I also did have some slight nausea, nothing bad enough for me to be concerned.

I have heard from others that taking it at night is good because then you can go to sleep if you have side-effects, but to do it a bit before you are ready to go to bed because if you have a rapid heartbeat it may interfere with falling asleep. I went to bed about a half hour after taking it and all was well. Hopefully it will continue that way but some people don't get bad side-effects for a number of months.

I am very hopeful. If I do have side-effects I can easily discontinue it, but I hope that does not happen. It's just so darned expensive. I am on Medicare so I used their website to find the drug plan that would be best for the drugs I am taking. That led to a change in drug plans, saving me about $800 a year! The new drug plan does have a hefty deductible though so the first month cost me $900. It will be about $500 next month I think and stay there until I hit the donut hole at which point it will go up, and then down quite a bit when I come out of the other side of the donut hole. I went through this xifaxan when I was pre-transplant too so I am familiar with the coverage.
JK