@rosemarya, @contentandwell, @jodeej, @jolinda, @ca426 and others,
Medication discussions can offer great advice to everyone, but we always suggest that anyone, regardless of the medication type, check with the team who is caring for you for recommendations on how and when to take your medication before you make any alterations to your meds. Our nurses say that most medication is better tolerated with food. Mayo Clinic doesn’t offer a preference for taking immunosuppression medications with or without food in general, but we do recommend that patients be consistent, because switching back and forth between with and without food can change the absorption of the medications, particularly of tacrolimus. Again, please don’t make any changes to your medication routines without first checking with your personal transplant team.