I spent 8 years on Seroquel 300mg each evening, worked so good for many years. The long term effects are ever lasting as stated in the four pages of warning from AstraZeneca. I have lived in depression for several decades playing games with prescription's and healthcare. Prescription free now for the past month and it is horrible and I guess as many doctors told me, You can not ever stop taking this Seroquel. Seroquel is for those who want to continue health issues and have lots of extra cash and insurance. Read the fine print with this drug and yes its all true... I have been so sick I can not even think about depression anymore. Good days and bad days one day at a time. You decide your health not others who are in it for the money and not for your well being.