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Getting off of Seroquel

Depression & Anxiety | Last Active: 5 days ago | Replies (722)

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@highserotonin30

Thanks for the help. I want to stop taking it because I've gained almost 90 lbs since I've started my treatment. It seems to me that at this point, the negative health consequences far outweigh any antidepressive qualities the Seroquel has had on me. I'm still depressed and very anxious. The only exception is that now I also have about 80 extra pounds to show for it. I'll make sure to check out those other discussions.

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Replies to "Thanks for the help. I want to stop taking it because I've gained almost 90 lbs..."

Hi, @highserotonin30 - I wanted to add my welcome to Mayo Clinic Connect. I experienced weight gain from taking citalopram (Celexa) about 8+ years ago, and that was very frustrating. I would say that for me, the weight came off semi-easily after I was tapered off of it.

I'd also like to invite @pharis022 @parus @freddymercury @maclodge to offer any insights they may have related to tapering off of quetiapine (Seroquel) and also weight gain with this medication vs. its antidepressive qualities. @jakedduck1 @johnbishop may also have some thoughts to share.

Since you mentioned you are still depressed and very anxious, what does your doctor plan for your treatment after this taper is done, @highserotonin30?

The weight gain is a nightmare. I also got high cholesterol and joint problems from the weight gain. I'd rather find other ways to sleep than deal with seroquel's "moderate" weight gain (according to the seroquel literature, it only happens to a small percentage of people, but everyone I have spoken to online and in person has had a big weight gain).