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DiscussionHigh Levels of Vitamin B12 and Ferritin: Any pointers?
Blood Cancers & Disorders | Last Active: Jan 23 7:55am | Replies (112)Comment receiving replies
Replies to "I just recently received mine back and it read that my B12 was 1708 .. I'm..."
I think you need to ask your doctor about this. Maybe ask them to redo the test. I see my doctor Monday and I am going in with medical articles that talk about high B12 and what could be causing it. In addition to what might be causing it, I have read that high B12 is functionally low B12 because it means your body is not utilizing and it is also not being eliminated.
Hi, I hopefully have some answers for you...and many of you! I also have been trying to figure out the causes of my high B12 for the past four years and after the diagnosis of a rare, genetic disease called, MEN-1 (Multiple Endocrine Neoplasia - Type 1), in early 2018 which is a form of cancer in that it causes tumors throughout my endocrine system, some are benign, some malignant, I thought I finally had the answer. Turns out I was wrong, and to date, this disease is not the cause of my high B-12. That said, I'll admit I was the slightest bit disappointed to learn this particular disease had nothing to do with my high B12...and as my health has continued to decline despite surgeries to remove tumors (the only way to battle to this disease), I have been digging even harder to find the cause of the elevated B12 knowing there IS one! I too have heard from ALL of my physicians, many of whom are quite brilliant, very well-respected, published doctors at major medical institutions such as Mayo, MD Anderson and Baylor that, "there is no clinical significance to my high B-12" when my lab reports come back! Well after four years and me requesting it be checked at least once or twice annually, (each time it has gotten a little higher...yet there's NO SIGNIFICANCE to that???!!!!) Come on already!
So here is what you need to know: Vitamins B and C are water soluble and any surplus of these vitamins is excreted in the urine. Vitamin C and all of the B vitamins -- thiamine, riboflavin, niacin, vitamin B-6, folate, vitamin B-12, biotin and pantothenic acid -- share similar characteristics because they are all water soluble. The body has a limited ability to store these vitamins so they need to be continuously replenished by the diet. Water-soluble vitamins are absorbed by the digestive tract into the blood stream, metabolized and then excreted by the kidneys in the urine.
Knowing that, here is what you need to look up, and it's right here on the MAYO website, it's on Livestrong, MD Anderson, Healthfully, WebMD, etc... Just google: "causes of high vitamin B-12 levels in the blood"
Here is what I have: a rare blood cancer called, "Polycythemia Vera"
I forgot to mention that I normally have low Red blood platelet count. Which if I use any form of pain medication depletes it almost completely. I've had Tests done for my Liver so it's not that. But I have asked about possible VIII as it runs in our family.I have a life long history of anemia .