Weight Gain with Evenity

Posted by susanew @susanew, Feb 11, 2025

Some have said they gained some weight when taking Evenity. Any idea at about what shots you noticed this? I am now going to be taking shots #9 and I do notice about a 4 to 5 lb. gain. Anyone else notice a gain in weight and if so, when was it noticeable?

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My endocrinologist wants me to start Evenity as well. I am concerned with reading so many people’s experience with gaining weight while on this drug. I have been on GLP1 for over 3 years for several medical issues and will remain on these drugs for life. My question is—is anyone that has been on Evenity or currently on it also taking a GLP1 as well? If so, did you gain weight taking Evenity while on your GLP1? Can you please share your experience? Thank you kindly.

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Profile picture for slh6284 @slh6284

@coinholio are you able to make any progress getting the weight off after finishing the injections? Also, what drug did you transition to after finishing the Evenity? Just trying to gather info from others and be prepared when the time comes.

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@slh6284 I haven't been off the Evenity for even one month yet. I followed up with Reclast, which has a huge list of side-effects, including weight gain. I am not concentrating on getting the weight off, I'm just going to see what happens naturally.

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Profile picture for sandrac @sandrac

Yes, I had a gradual weight gain of about 7 lbs after about the 4th month. But, I am finished now and my gains ranged from 4.7 to 8.5 in lumbar spine, femoral back and hips. Have 30 more days before it is out of my system but my weight is beginning to creep back down to normal with my usual Mediterranean diet. My lumbar spine is in normal range and the others areas are in osteopenia range but doctor says it is pretty normal at age 75. Evenity was worth it for me!

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@sandrac I also am experiencing some weight gain on Evenity without altering my eating habits. I am very frustrated about it because I am very weight conscious. I am not very active. I am 82 years old. But my weight remains a consistent 122 to 123 pounds. I am 5’ tall. Now I am closer to 126 pounds. Can you please tell me what you eat on the Mediterranean diet? It has been recommended to me by my physician. Thank you!

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The weight loss, back to my normal weight, did really start to happen until I was done with my year of Evenity. The Mediterranean diet can be looked up online for best options, but basically we eat very little red meat, lots of fresh vegetables, occasionally pasta but we generally limit carbs/ bread to no more than three servings per day. We also do not eat after 8 pm and if possible, eat an early dinner around 5:30. For exercise, walking is helpful even if that is all you can do. Good luck to you. Try not to be too o discouraged. Your bones are important!

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I have taken 6 months of Evenity and have gained about three or four pounds. Every month I gain a couple of pounds and have to fight to get it off, but there is still a gradual increase in my weight. I do aqua aerobics 5x weekly and my eating habits have not changed. As someone who has struggled with being overweight by at least 20 pounds my whole life, this is very discouraging. Now I’m starting to notice joint pain, especially in my knees. I had to discontinue Prolia because of severe jaw pain, and immediately had four compression fractures in my spine and two surgeries. Twenty five months of Forteo caused me to go from osteopenia to full blown osteoporosis. I am at a loss at what to next next.

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Profile picture for vegada @vegada

My endocrinologist wants me to start Evenity as well. I am concerned with reading so many people’s experience with gaining weight while on this drug. I have been on GLP1 for over 3 years for several medical issues and will remain on these drugs for life. My question is—is anyone that has been on Evenity or currently on it also taking a GLP1 as well? If so, did you gain weight taking Evenity while on your GLP1? Can you please share your experience? Thank you kindly.

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@vegada ojalá ganará pedí . Quisiera yo no he experimentado nada. Me falta pero a partir de que dosis notaron

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I am having #4 shot this coming Friday 10/16/26 and I noticed that i gained weight. My PCP checked my weight and since July 2026 i gained 20 pounds. I will consult with my rheumatology doctor who is putting me the infections to see what he thinks.

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