Connect← Return to What is the difference between Octreotide and Lanreotide?
Discussion
What is the difference between Octreotide and Lanreotide?
Neuroendocrine Tumors (NETs) | Last Active: Jun 9 2:51pm | Replies (24)Comment receiving replies
Hi, I have been on Octreotide for 4 years but my oncologist might prescribe me Lanreotide. I had my fourth operation on 11/10/2025 where the doctors had to remove my terminal ileum because of the obstruction caused by adhesions, which has led to an increase in my diarrhea.
Do you think changing the injection would help with my diarrhea?
I would really appreciate it if you could share your experiences.
Yasemin
Replies to "Hi, I have been on Octreotide for 4 years but my oncologist might prescribe me Lanreotide...."
For me Lanreotide didn't work in relieving my Carcinoid Syndrome, Ocreotide did..
Hi Yasemin. Since your diarrhea became significantly worse after your terminal ileum was removed, I would ask your doctor specifically about bile-acid malabsorption before assuming that changing from octreotide to lanreotide will solve the problem.
Good day to you. I had my ascending colon, and ileum valve removed 21 years ago. I had unexpected diarrhea for a few years. Eventually my body adapted, meaning I could usually find a bathroom. I think my body adjusted. Bowel movements for me then usually came about 10-20 minutes after a meal. I'd try adjusting how much and what you eat to see if that changes your situation. Good Luck it's not easy but i hope you find a quality of life that is acceptable to you. Good Luck. Your body is amazing so help it recover. I also stopped alcohol which seemed to help.
Connect
This is a good question and one worth asking and finding the right decision for each person.
Here is a link to the discussion which addresses your question:
https://connect.mayoclinic.org/discussion/octreotide-or-lanreotide/
Your NET specialist is probably aware of the NIH (National Institute of Health) study which compares and contrasts Octreatide and Lanreotide. https://pmc.ncbi.nlm.nih.gov/articles/PMC12120025/
After discussing with my NET oncologist I chose the Lanreotide shot. It came down to the NET specialist opinion and my willingness to find out which works better with less side effects for me.
I know that adding Creon to whichever shot, helped with the diarrhea for me, so a discussion with the NET specialist was the best idea. My local Doctor had only given out Ochtreatide but gave me Lanreotide after discussion which has worked out.. I was told that if it did not work, we could try the other..
Wishing you peace of mind and a doable shot with whatever you come to take.