1. < Polymyalgia Rheumatica (PMR)
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Extremely tired before PMR diagnosis

Posted by maryjanecowell @maryjanecowell, Sep 23 6:58pm

Is there any correlation with earlier fatigue and PMR (before prednisone given) ?
My husband started feeling fatigue about 2 or 3 months before showing pain symptoms in his wrists and subsequent diagnose of PMR. Of course the fatigue has gotten worse with the prednisone but I’m curious if we might possibly be able to “blame” PMR for the early fatigue. Thanks and please know that I, the spouse, so appreciate all these posts. Giving each other support in this journey is so helpful.

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maryjanecowell | @maryjanecowell | Sep 26 11:36am
In reply to @cwbf "If my experience is indicative, fatigue might indeed mark the earliest stages of PMR. While on..." + (show)
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If my experience is indicative, fatigue might indeed mark the earliest stages of PMR.

While on a vacation trip to Hawaii with family, one January, I became overwhelmed by fatigue and spent most of each day in bed sleeping and resting while the family were at the beach. By February I felt acute pain in my hips and shoulders and had trouble putting on a shirt. In March/April I was diagnosed with PMR. I had never thought that the extraordinary fatigue I experienced in January might have been a precursor to PMR but now it seems possible, if not likely. Thank you for your excellent question.

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@cwbf So sorry you experienced such fatigue also but hopefully because if all these comments, you know that PMR probably started the fatigue and not something else. Be well.

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cwbf | @cwbf | Sep 26 4:42pm

Thank you for your helpful observation. I have been on Kevzara for 9 months, feel much better and perhaps the end is in sight.....

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rosi75 | @rosi75 | Sep 26 7:33pm

Hi @maryjanecowell

Perhaps someone has mentioned this already but the following paper mentions a correlation between low serum glutamate and fatigue in PMR.

Not sure if that's of any help, just wondering if it's worth asking rheumatologist if they think supplementation or perhaps eating foods high in glutamate may help with the fatigue? So long as it doesn't conflict with anything else. Something to maybe explore.
https://pubmed.ncbi.nlm.nih.gov/38797046/

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