Am I the only one that’s in denial?

Posted by indenial @indenial, Sep 18 10:26am

Is there anyone else in this group that refuses to start treatment? I’m 62 years old with a T score of -3.8 in hips and spine. Even though I’ve just suffered a painful compression fracture, the alternative (Meds) still scares me to death. I feel like I’m too young to start treatments that will cause rapid bone loss the minute you stop medication. I realize you go on to a second medication to lock in the gains, but then what?? At 62 years old, the treatment sounds more terrifying than the disease itself. I’m doing all the natural things in the meantime and awaiting a new DEXA scan. I did have a slight improvement on my last one, this was mainly from collagen peptides, calcium, D3 with K2 and walking on treadmill. I know I should have added light weightlifting to the regimen, but hindsight is 2020. When I am fully healed, I plan to go that route as well. I’ve read all the pros and cons to every single medication on the market and the cons, for me, seem to outweigh the benefits. Am I alone in this thought process?

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Profile picture for pamstarr @pamstarr

@summera1
I meant this as a reply to you lol
Wow - sounds like you are doing all the right things! When I saw you were on Tymlos I said - yes! I too, was in denial for years and felt that using the stairmaster weight training nutrition would all be enough but over the last six years I have deteriorated quite a bit. Due to another condition, I had to go on long-term high-dose prednisone so it was one of the first issues my rheumatologist brought up. Honestly, I am so happy at the potential for actual bone building at this point after all these years being afraid of the side effects of the standard meds. I see how prevalent fractures are and feel blessed that so far I have escaped! I am actually doing a short course of physical therapy to be best informed as to the exercises that will really help me without causing harm as you said, no twisting, etc.. I have a long history of going to the gym starting back in the day with spa lady lol! So I applaud your efforts and wish you much success!!

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@pamstarr Thanks, I used to go to Holiday Spa back in the day:)

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Profile picture for boneoptimist @boneoptimist

@wilweten , honestly if I can't maintain whatever BMD I get to (in this next year on Tymlos) by keeping my routine up after stopping Tymlos, Evenity might be what I'm leaning toward. So much can change in a year, so I will start heavier research on my end in about 6 months, and hope that new studies/research come out meanwhile that can guide me. Fingers crossed!

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@boneoptimist exactly! I was so hoping that something new and improved would come out, before I had to choose between what’s available today. Tymlos definitely sounds like the gold standard, but it’s the years following that scares me.

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I didn’t have much luck with AlgaeCal or Bone Up (lol, I know!) Currently on supplements from Healthy Bones Co.. Feel like it’s all just a bandaid though

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Profile picture for boneoptimist @boneoptimist

@jenben59 , don't get me wrong, I'm talking about looking for the drug after the one I'm on, if I didn't make that clear. I'm getting excellent results on Tymlos and hoping (and working really hard) to get to normal bone density in the next year. I went from severe OP to OP, and now into osteopenia, so I'm very hopeful.
Good luck in your bone journey!

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@boneoptimist, did you have any severe side effects from any of the bone medications? I went to my doctor, had a DEXA scan, was diagnosed with osteoporosis, and was prescribed Fosamax. Side effects do not occur in all women, but I get concerned about the pain and the possible dental problems. I had cancer, and my gums/teeth have problems. I do not want to be in pain or cause myself any medical problems unless there is a positive outcome with few side effects. From what I read, there is not always a good outcome, and some women have to try different medications to find one that works without pain or with very few side effects. I hope everything works out well for you.

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Profile picture for jenben59 @jenben59

@boneoptimist, did you have any severe side effects from any of the bone medications? I went to my doctor, had a DEXA scan, was diagnosed with osteoporosis, and was prescribed Fosamax. Side effects do not occur in all women, but I get concerned about the pain and the possible dental problems. I had cancer, and my gums/teeth have problems. I do not want to be in pain or cause myself any medical problems unless there is a positive outcome with few side effects. From what I read, there is not always a good outcome, and some women have to try different medications to find one that works without pain or with very few side effects. I hope everything works out well for you.

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@jenben59 , Hello! So if you can, please watch the video about drug sequencing. In summary, drugs should go like this: bone builder (anabolic- like Forteo or Tymlos) first, then a builder combined with a bone conserver (like Evenity), then last is the bone saver like Fosamax. The bone savers actually can block the bone builders for quite a while (months, years), so see if your Dr can get you on a builder first. Here's the video:


I've been taking Tymlos for 11 months (daily injection in the lower abdomen). The first injection made me flu-like sick, in bed for 2 days, slight fever, and vomiting. I called the Dr, she told me to start out at a lower dose. I started at one click (1/8 of a full dose) for like 5 days, before going to 2 clicks for a few days, etc. When I got to 6 clicks, my heart raced for a few hours, Dr had my calcium checked, it was too high. She had me take a week off, retest calcium, then I started at one click again.
After 4 months I basically stayed at 5 clicks. When I tried 6 clicks, my heart rate would rise to 165 BPM in my SLEEP, and that was 8-9 hours after injection. Dr said that I might just have to stay at 5 clicks. I still get occasional headaches/head pressure from it. I've learned to drink a lot of water before and after injection. And I pee a lot because of it.
In spite of the low dose, my bone density in spine has improved 5-7% every 6 months, so the drug is worth the hassle. I do a LOT of exercise (weight lifting and treadmill and pickleball) and nutrition/supplements too. I have friends just doing injections and taking calcium, and they are not getting the same results.
After Tymlos (2 years total), another drug is the standard protocol.
Good luck in your journey, and I'm happy to answer any questions! The posters here have a lot of collective experiences, so you will learn a lot!

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Profile picture for summera1 @summera1

@randysarner I was told I must start with a -3.9, but my endo did allow P1NP and CTX blood tests, before weight lifting, one month later, to compare. I had no improvement, in fact, more loss. However, I had not progressed much in one month with weights. I now lift MUCH heavier, but I still want to get better. I think improvement does not really show until you can lift over fifty pounds. I am at 25. I have read of people going from osteoporosis to osteopenia with weight training, but they do not say if their numbers were as bad as ours. My thought was to keep lifting for life. I figure that with Tymlos and weight lifting, I can get my bones as strong as possible. I am hoping that weight lifting might be able to keep me off meds after two years on Tymlos. Time will tell. If you add weight training, get help to lift with correct form, and do not add jumping with a -4 score. I only do heel drops and sometimes a jump off a standard step. I had pain trying to do jumping jacks or jumping rope. As far as exercise, you need upright exercise. So, biking and swimming not so much. Google for correct bone exercising. There are great sites out there. AVOID any lifting WITH twisting and AVOID any spine flexing except a mild bend or twist without weights. I feel so much stronger and healthier with lifting. I was walking 10,000 steps a day for years and it did nothing. Good luck! I have my DEXA Oct 8th. It will be five months on Tymlos and five months weight lifting. I starting weight lifting one month before Tymlos, but had to stop weights for one month during that time because I was hurt. I do not think it was the weight lifting. I had a really bad attack of sciatica, which I have had before Tymlos or weight lifting. (I have bulging disks and stenosis for a very long time)

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@summera1 , Hello and great job on the physical exercise! I really think the exercise/Tymlos combination is very necessary. Like you, I want to get the most improvement while on this drug because the other drugs scare me.
You questioned t-scores in going from OP to osteopenia with just exercise. I'm a data/numbers person and I track lots of things , so here are the numbers. I started at -4.1 in my worst area (L-4).
Over 19 months of just weights, pickleball, nutrition, protein I got that to -2.7. Other areas did make it into osteopenia. Unfortunately my femoral neck was unchanging at -2.7, and Dr didn't think the progress was fast enough, so she said time for meds. On Tymlos, I do a dexa every 6 months, so i know the progress is steady at 5-7% improvement in BMD every 6 months. The -2.7 went to -2.2 and -1.8 while on Tymlos (6 month increments). I added leg slams/stomps to my routine in the last 6 months (that I kinda made up myself, out of desperation), but they finally got the needle to move on femoral neck density, improving 6.46% BMD, and t-score from -2.7 to -2.4 on one side, -2.7 to -2.5 on the other.
I agree with your effort to increase the weight you use. I do the same. I'm always increasing either reps or weight. I think you are really going to see improvement on your next dexa. I assume you have the nutrition component covered as well?
I recognize your hard work, and I wish you the best!!

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Profile picture for memuno1stborn @memuno1stborn

Sometimes we need to just listen, sometimes it helps to hold someone's hand, and sometimes we just need to tell it like it is. Honestly, I don't understand why people play Russian roulette with their health. You're young (I'm nearly 80 yrs. old) and osteoporosis could shorten your life. Get over yourself about taking medications. It's important to work with your doctor and not simply look to others for medical advice or give credence to bad experiences of others.
In November 2025, I was diagnosed with severe osteoporosis. I lived in a fool's paradise thinking that an active life, healthy diet, healthy lifestyle, supplements, BHRT (bio-identical hormone replacement) would prevent osteoporosis. I don't smoke or drink and mostly stay away from processed foods. It's an absolute miracle that I never experienced any fractures given my activities (cycling, running, hiking, gardening, walking). Two years before I had a total hysterectomy and was literally bent backwards throughout the procedure and most likely already had osteoporosis.
Full disclosure: I have taken BHRT for over 30 years and progesterone is a component. I found out that progesterone aids in sleep and helps alleviate Tymlos side effects. I take BHRT meds at night just before going to bed and my body works through the Tymlos side effects while I sleep.
True story: when I found out that I had to take Tymlos and self-inject it on a daily basis, it freaked me out and I asked if there was a pill that could be taken as an alternative. While the endocrinology nurse was preparing to show me how to self-inject, she quietly spoke and said, "At your age, I'll bet you've had to deal with a lot of hard things in life." I responded, "Yes, indeed I have." That's when she said, "OK, this is just one more." I suppose some people might have been offended, but I laughed so hard because she was right!
I totally understand your fears and concerns because I'm the same way about medications. Every action we do or don't do has consequences. We have to decide which consequence(s) we're willing to live with. Osteoporosis is not curable but can be improved. I absolutely hate the daily injections, but I have a strong survival instinct and chose life and a reasonable assurance from the doctor that Tymlos would help grow bone and prevent further spine deterioration--and it has. Nearly a year later, the severe osteoporosis has improved and I've achieved osteopenia status. I'll gladly accept this and am thankful that the severity of my osteoporosis was discovered and saved this old lady from a painful future.

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@memuno1stborn thank you for your candid response! I’m glad you overcame being freaked out about self injections! You never know when that skill will come in handy! I did Forteo years ago and then had to dust those skill off to do injections of Lovenox!

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Profile picture for memuno1stborn @memuno1stborn

Sometimes we need to just listen, sometimes it helps to hold someone's hand, and sometimes we just need to tell it like it is. Honestly, I don't understand why people play Russian roulette with their health. You're young (I'm nearly 80 yrs. old) and osteoporosis could shorten your life. Get over yourself about taking medications. It's important to work with your doctor and not simply look to others for medical advice or give credence to bad experiences of others.
In November 2025, I was diagnosed with severe osteoporosis. I lived in a fool's paradise thinking that an active life, healthy diet, healthy lifestyle, supplements, BHRT (bio-identical hormone replacement) would prevent osteoporosis. I don't smoke or drink and mostly stay away from processed foods. It's an absolute miracle that I never experienced any fractures given my activities (cycling, running, hiking, gardening, walking). Two years before I had a total hysterectomy and was literally bent backwards throughout the procedure and most likely already had osteoporosis.
Full disclosure: I have taken BHRT for over 30 years and progesterone is a component. I found out that progesterone aids in sleep and helps alleviate Tymlos side effects. I take BHRT meds at night just before going to bed and my body works through the Tymlos side effects while I sleep.
True story: when I found out that I had to take Tymlos and self-inject it on a daily basis, it freaked me out and I asked if there was a pill that could be taken as an alternative. While the endocrinology nurse was preparing to show me how to self-inject, she quietly spoke and said, "At your age, I'll bet you've had to deal with a lot of hard things in life." I responded, "Yes, indeed I have." That's when she said, "OK, this is just one more." I suppose some people might have been offended, but I laughed so hard because she was right!
I totally understand your fears and concerns because I'm the same way about medications. Every action we do or don't do has consequences. We have to decide which consequence(s) we're willing to live with. Osteoporosis is not curable but can be improved. I absolutely hate the daily injections, but I have a strong survival instinct and chose life and a reasonable assurance from the doctor that Tymlos would help grow bone and prevent further spine deterioration--and it has. Nearly a year later, the severe osteoporosis has improved and I've achieved osteopenia status. I'll gladly accept this and am thankful that the severity of my osteoporosis was discovered and saved this old lady from a painful future.

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@memuno1stborn I totally agree. I used Forteo for 24 months in 2016 and have just completed a second course of 24 months now. May I ask what you are using for maintenance drug after Tymos? I can no longer measure the density in my spine due to a series of fractures before my first treatments with Forteo. I have not fractured since. There has been improvement in my hip density, and as Forteo mainly boosts the spine, I can only pray and assume even better scores there. I will be 69 in December. non smoker and no alcohol. Active healthy life style, but do have Lukopenia so crappy hemoglobin and nutriphils.

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Hi , I’m 57 yrs old was diagnosed with osteoporosis last year and also don’t want to use prescription medication for all the side effects. I listen to every podcast in you tube to educate myself about medication side effects and what else to do instead of prescription medication. Last night I found this great and very informative podcast call the “fragile truth about bone health and Dexa . Please everyone listen to it . You will change your mind about medication. Also ask your Dr about your Frax Score which will tell you the possibility of a hip fracture in the 10 yrs of you life . Very important.

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The interview is interesting. It is true in the UK that osteoporosis patients have to see a rheumatologist in order to get script for Forteo, but in the US primary care physicians can and do prescribe these meds. I'm not sure that is altogether positive, though.
Romosozumab is limited to one year because it usually becomes antiresorptive at one year starting the switchover at 6 months.
https://news.weill.cornell.edu/people/dr-lisa-mosconi
https://integritywellnessmd.com/does-hormone-therapy-increase-the-risk-of-blood-clots-or-stroke/
While the interview doesn't change my mind about the usefulness of medication with osteoporosis. I think we should look at all the information (with a little suspicion) before making a decision about these medications.

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