This is the $64,000 question. . .WHY NO MED FOR NEUROPATHY?

@empresskristine it's hard for me to imagine what to are going through. I have neuropathy that came out of nowhere over two years ago (the symptoms started right after I had Covid that they said was a new strain at that time so this may me the result of long term effect of Covid). It has progressed and become more and more severe. It is affecting my legs and now my arms - pain, burning and weakness. The Lyrica is no longer effective. The neurologist suggests adding Cymbalta but I am hesitating because of the side effects plus it interacts with the blood thinner I am taking for atrial fibrillation. Then only thing that helps me sleep is melatonin. I started with 3 mg but now I am down to 1 mg bf bedtime that I found is enough to give me enough hours to sleep and the pain doesn't wake me up. I feel sympathy for your pain and hope you find relief. I live in small town IL.

Some one posted a vido about 3-4 weeks ago that answered the question you raised. I am so skeptical of everything these days being Ai generated, that I almost didn't watch it but found it did make sense. He is a researcher- who is working on neuropathy and is lacking funding since his belief is, neuropathy is considered incurable so there is no profit angle. He also wondered why the many of us who suffer from neuropathy are not demanding that funding goes to neuropathy research. He indicated that we suffer in silence so few know how severe a problem neuropathy is ,and how many of us there are. As I said, knowing how profit is a huge motive for funding anything - think weight loss drugs = I found him to be very believable . Maybe the person who posted that video can post it again.

@revdorth
I live in Texas and went to see Dr Anne Oaklander in Boston. She has lectures and medical research papers. Diabetic neuropathy is what the doctors go off of with the most research. There are a lot of research neurologist. One size does not fit all with different causes. Her mother was a research neurologist, she is a research neurologist along with her daughter.
The problem the majority fall under diabetic neuropathy, then you have idiopathic, medication induced and least autoimmune which is mine. Try to find documentation on autoimmune neuropathy very little. The foundation of peripheral neuropathy just granted researchers grants. Did he apply?
https://m.youtube.com/watch
https://m.youtube.com/watch
https://www.foundationforpn.org/

@artemis1886 I have listened to her lecture (the one on YouTube you recommend) many times and she is definitely renowned for her work in SFPN. However, this lecture is 8 years old, and I’m surprised that there aren’t any more current lectures available. We are all waiting and depending on her, but we’ve been waiting for some advancement for a long time. It’s a shame the funding, $$$$, isn’t there to delve into more research.

@artemis1886 I have listened to her lecture (the one on YouTube you recommend) many times and she is definitely renowned for her work in SFPN. However, this lecture is 8 years old, and I’m surprised that there aren’t any more current lectures available. We are all waiting and depending on her, but we’ve been waiting for some advancement for a long time. It’s a shame the funding, $$$$, isn’t there to delve into more research.

@jchet I have lost my link to a recent article, but the gist of it was that one of the biggest limitations in clinical research right now is the lacking of willing participants in clinical trials.
For many medical issues, the funding is there, the research is ongoing, but trials struggle to enroll enough participants. One study on bronchiectasis, an uncommon lung disease was only able to recruit fewer than 50% of their patient goal.

Here is how to find neuropathy clinical studies you may be able to participate in to advance the science:
https://neuropathyresource.com/neuropathy-clinical-trials/

You are not asking too much. I was there with all they can do was give me Lyrica or gabapentin. I was on a very low dose of Lyrica and was so fatigued I couldn't walk to my car. Then my husband died and had to deal with that but later on I read on this website that alpha lipoic acid 600 mg made by Source Naturals helped plus a good B complex vitamin (B12 helps even if your B12 is normal as your body pees out what it doesn't need). Anyway, long story short within a short time can't remember how long but not long am 90% better - take the two of them every morning. It was a Godsend. Found out later the dr I was seeing didn't know about this product and has left the clinic but the other one did. He took special ed or training for this and knew it helped. See, the bottom line doctors don't study supplements. I went to a nature store and the owner takes it too and had only one bottle left - LOL - he said "can I hold it for you." LOL, boy he made my day as I had pins and needles throughout my body, numbness, burning and it all. TRY it what do you have to lose and don't take that awful medicine. Good luck and God bless. It's hell having neuropathy.