PSA increase

what is your history with prostate cancer?

if none, then you are well under 4 PSA which is on the good side. But obviously your PSA is rising ( doubling) ..might want to get under good urologist care and maybe get MRI and see what is going on , if anything

This is probably a problem. If you’ve been treated by having a prostatectomy initially, then you are way past when you should’ve been treated. If you have radiation as your primary treatment, then you are just at the point where you really need to get something done. You should be seeing a Genito urinary oncologist, They are the ones that specialize in prostate cancer.

You should be going to a center of excellence since your PSA has risen so much.

If you’ve never had prostate cancer, and your PSA has just been rising, it may not be a big deal. But it’s still within normal range for a person up to at least 70. You could always ask your doctor for an MRI if you are worried.

If you are still in your 50's than it is probably a problem. PSA going up 300%+ in 2 years. Get a urologist to provide further testing. May do another PSA with free PSA. If they are suspicious may do more non-invasive tests or go straight to mpMRI. If you have been treated for prostate cancer in the past it is definitely a problem.

If you have never been diagnosed or treated for PCa a jump of .75 in a year's time, with that jump putting you over 4.0 is the recommended time for a trip to the urologist. With that said, if my PSA had doubled in a year's time, and or increased 300% over 2 years, I would ask for a referral. My PSA was only 4.37 but had jumped 1.15 in a year, I was diagnosed with Gleason 8, with cribriform and IDC 4 months later, which means my PCa is very aggressive and high risk. Fortunately I didn't wait another year for my next PSA test.

@toddfather11
Really good question and really depends on what treatments you had. Did you have RP? I did not have RP or hormone treatments so cannot comment on personal experience with those treatments and expected numbers. My PCP (Mayo) told me they use the sensitive and ultra sensitive PSA test on those who have had RP.

I can comment on my experience with PSA jumping around if you had radiation. My R/Os, urologist and PCP all said to expect bumps of my PSA numbers. And they begin to become concerned if a continue rise not just an isolated bump here and there. And sure enough I had one bump in 3 years since the end of my treatments.

What did you doctors tell you about your increasing PSA numbers? You do have a ongoing rise and if me would be asking my doctors for medical feedback. I can't post my experience with what your numbers should be only what my R/Os told me about my specific numbers to expect after my radiation treatments ended.

I do know my UFHPTI R/O said goal was to keep my PSA below 1 I am well below that now with an non detectably PSA number. I would suggest contacting your urologist who did surgery and or whomever is ordering your PSA tests about the continued rise.

Seems a big jump like that should get some further testing. I had a big jump almost double, but still stayed below 4, PCP said no big deal it's under 4. I thought that it wasn't good, but screwed up and listen to PCP. About 18 months later semen had a bit of blood. Went to urologist and long story shortened up had prostate cancer moderately aggressive with cribforms. Had prostate removed and pathology shows good chance of BCR.
What does UFHPTI mean in above post?

@diverjer U. Florida Health Proton Therapy Institute

@diverjer
Sorry @diverjer I sometimes forget about abbreviations.

UFHPTI: University of Florida Health Proton Therapy Institute. It is located and Jacksonville Florida. A huge complex with 5 Proton Gantries. They have been doing proton radiations since 2006.

@jim18
Ooops, @jim18 did not see you had already answered @diverjer

@toddfather11
If you have not been treated before for Prostate Cancer, you might want to get the blood test made by Oxford Biodynamics called the PSE test. It tests five bio markers and with 94% accuracy shows whether you are likely, or unlikely, to have prostate cancer. For comparison purposes, the PSA test alone is only 55% accurate. Here is the link to their product webpage:
https://www.94percent.com/