Hello @dhafford, Welcome to Connect. I'm hoping your upcoming appointment will finally provide some guidance and a treatment/management plan to help you get some relief from restless leg syndrome. It sounds like you have tried a lot of different treatments without much relief. Have you tried any of the lifestyle and home remedies or coping and support suggestions listed on the Mayo Clinic site? - https://www.mayoclinic.org/diseases-conditions/restless-legs-syndrome/diagnosis-treatment/drc-20377174.