Day off after Reclast?

Posted by janism @janism, 3 days ago

This feels like a trivial question, but, there is such a deep well of experience here...

I am a teacher and about to start Reclast. I have the day of the influsion off (for Yom Kippur--sounds like the infusion is nasty enough that it could help me atone for the year's sins) and was wondering if I should take the next day off. I want to decide ahead of time so that I don't have to write lesson plans when I'm miserable. If you have been on Reclast, how did you guys feel the day after your infusion? Figure a scale that looks like this:

Normal for me

Achy, like mild cold or flu

Just want to sleep or watch a bad show, like a bad cold or flu

Completely Miserable

Death warmed over

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

Not trivial at all. I'm sure you will get many answers. Have you done a search for prep advice? If not search preparation for reclast injection or infusion. I may be getting reclast and I paid particular attention to having you doc order a longer infusion an saline drip.

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Hello, I hydrated before and after. Also took 2 Tylenols an hour before infusion and had it administered over 40 minutes.
This was my 3rd one. No side effects. I took it easy the next day just as a precaution and took 2 Tylenols every 8 hours the next day. Hope this helps.

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Drank water as instructed. No side effects.

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janism, it depends upon how bad you've been. You may need a few days, a week, or a year of atonement. We can't give you an accurate assessment until you tell us what you've done.
I haven't taken Reclast, but I know this really sweet bone specialist who offers the advice given by gravity--a longer infusion and the advice given by tillymack--fluids and chanduk--fluids and tylenol. Some clinics (in Korea) administer steroids before the injection. loriesco has her steroids in hand just in case. I'd say take the day off and we'll hope that you don't need it.
It seems that people with autoimmune systems fare worse than those without. Here's from the Stanford doctor who doesn't mention steroids, but is otherwise quite interesting
"A opposed to administering the 5 mg of zoledronic acid in 100 mL of D5W and infusing it over 15 minutes, for the past 29 years I have had the infusion nurse at Stanford dilute it into 500 mL of NS, and to infuse the 600 mL of now diluted BP over 60 minutes. TRUST ME!! By diluting it and administrating it more slowly, it improves the renal (kidney) safety.
The othr thing I do is to instruct the infusion nurses to give the patient 650 mg of acetaminophen (Tylenol) during the infusion. Then I tell the patients to take that same dose (two regular strength tablets) with dinner and at bedtime the day of the infusion, with all 3 meals and at bedtime the day after the infusion, and a final (7th) dose with breakfast the 2nd morning after the infusion. This reduces the patient's risk of experiencing a symptomatic APR from >28% to < 1%."

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I am getting the longer infusion. My provider recommended hydrating and drinking something with electrolytes, ibuprofen, etc.

My question was really a poll--how many of you who have gotten Reclast were flat on your back the next day?

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Profile picture for chanduk @chanduk

Hello, I hydrated before and after. Also took 2 Tylenols an hour before infusion and had it administered over 40 minutes.
This was my 3rd one. No side effects. I took it easy the next day just as a precaution and took 2 Tylenols every 8 hours the next day. Hope this helps.

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@chanduk would you please share what your plan is after the third dose of Reclast?

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I guess my endocrinologist will check bloodwork and have me get the dexa scan and based on the findings will decide how to move forward. My 3rd infusion was close 20 months after the second one. That was based on the bloodwork. My doctor is very good. Hoping that I get a decent break before he decides how to move forward.
I wish I had followed the doctor’s advice in 2014. I was so scared to get any treatment for my osteoporosis. Then in 2021 I had a fall and fractured my left hip.
It’s good to be informed and do the research and get feedback from others. But at some point we have to make a choice. I could have saved myself a lot of suffering and having the surgery etc……..
I hope things go well for you. Good Luck!

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Profile picture for janism @janism

I am getting the longer infusion. My provider recommended hydrating and drinking something with electrolytes, ibuprofen, etc.

My question was really a poll--how many of you who have gotten Reclast were flat on your back the next day?

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I had my first Reclast infusion last September. I wasn’t told to take anything in preparation. I was given the 60 minutes infusion, and did okay the rest of that day. But the day after all I felt like doing was curling up on the couch—achy, lethargic, and very tired. I wouldn’t have wanted to be at work that day.

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All,

I've had more than my share of Reclast infusions, beginning c. 2011, and I've not had even a mild adverse reaction to them - I always, always, always, drink plenty of water before, during, and after the procedure and (probably ceremoniously) eat a small bag of pretzels while sitting in the chair.

I had my most recent infusion in July, and when the nurse asked if I wanted Tylenol, I said yes, although not sure why. I also noticed on the order from the doc that the infusion time was 20 minutes . . . wait, what!? When I called the infusion center, I was told that the protocol was 20 minutes, yet I remember the last infusion when I asked for 45 minutes I was granted that time (switch of insurance perhaps). Even with the shorter administration time for the med, I had no problems.

Face it, we are all rolling the dice on these meds - what works for one of us might not work for another. Wishing all a seven on the come-out roll!

Peace out! Cheers!

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Profile picture for gently @gently

janism, it depends upon how bad you've been. You may need a few days, a week, or a year of atonement. We can't give you an accurate assessment until you tell us what you've done.
I haven't taken Reclast, but I know this really sweet bone specialist who offers the advice given by gravity--a longer infusion and the advice given by tillymack--fluids and chanduk--fluids and tylenol. Some clinics (in Korea) administer steroids before the injection. loriesco has her steroids in hand just in case. I'd say take the day off and we'll hope that you don't need it.
It seems that people with autoimmune systems fare worse than those without. Here's from the Stanford doctor who doesn't mention steroids, but is otherwise quite interesting
"A opposed to administering the 5 mg of zoledronic acid in 100 mL of D5W and infusing it over 15 minutes, for the past 29 years I have had the infusion nurse at Stanford dilute it into 500 mL of NS, and to infuse the 600 mL of now diluted BP over 60 minutes. TRUST ME!! By diluting it and administrating it more slowly, it improves the renal (kidney) safety.
The othr thing I do is to instruct the infusion nurses to give the patient 650 mg of acetaminophen (Tylenol) during the infusion. Then I tell the patients to take that same dose (two regular strength tablets) with dinner and at bedtime the day of the infusion, with all 3 meals and at bedtime the day after the infusion, and a final (7th) dose with breakfast the 2nd morning after the infusion. This reduces the patient's risk of experiencing a symptomatic APR from >28% to < 1%."

Jump to this post

@gently Any chance you have or can find a link to those Reclast recommendations? My provider had previously mentioned considering a 1/2-dose of Reclast. At my last visit, she took a pic of the above Reclast recommendations that I had previously saved as a pic on my phone. It may give more weight to the recs, if I had a link that appeared more "official-looking" that included his name and affiliation, etc.

I just came across one of your previous comments about leaning toward a full-dose, being sure to incorporate the recs. I thought someone had mentioned more recent studies that one half dose was showing good promise and protection for 5 years. Am I not accurate with that or not remembering that correctly? Would you know?

I'm afraid my "less than 6 month"s on Tymlos may be coming to an abrupt end. As of this past weekend, I am developing "recall hives"....and a rash about 12 inches away from the injection area that may, or may not, be associated with a hypersensitivity reaction. Waiting now to hear from my health provider. I am so sensitive to most meds and Reclast is pretty terrifying to me, esp after having a severe delayed reaction to a previous oral besosphonate that I'm meticulously followed all the protocol for taking.

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