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Lupron: Anyone have muscle weakness and severe leg pain?

Posted by kam23 @kam23, Jul 14, 2023

I have PC and have been on Lupron injections every 3 months for 15 months. I am experiencing severe leg pain in hamstrings and glutes. Has anyone else experienced this or tried monthly shots?

This has been getting worse for the last 3-4 weeks. I’m afraid I’ll be in a wheelchair or have to stop this form of testosterone elimination therapy.

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dillon5520 | @dillon5520 | Aug 26 8:36pm

I was on lupron every six months for 1 year I complained following the very first injection of the leg pain 10-15 times a day and night lasting 3 minutes. Year 2 they reduced to half dose every 3 months there was some reduction in occurrence but still an issue. Year three on pill form occurrence increased. Treatment ended 9 months ago I continue to experience 10-15 times a day or night is this a rest of my life occurrence I am 82 my PSA is .004
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oesjipapa | @oesjipapa | Sep 4 6:15am
In reply to @narus "Testosterone gets a bad rap with prostate cancer treatment. It does not cause cancer but will..." + (show)
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Testosterone gets a bad rap with prostate cancer treatment. It does not cause cancer but will provide fuel that causes the cancer to grow faster. I have heard the phrase that Testosterone is like rocket fuel for Prostate Cancer I think a better analogy would be Lighter Fuel.
Have you had a Testosterone test?
Six months after radiation and Lupron my Testosterone was about 530 and I felt like crap all the time. After my first dose of T all the problems I was experiencing went away within a couple of days. My Urologist was strongly opposed to the treatment and denied that there was any downside to Lupron Treatment. I got a new Urologist who is agreeable with the treatment and not concerned.
If you take Testosterone your PSA will go up it is part of the biochemical process. I went from a PSA of .1 to .54 but it stabilized there.
Testosterone Is what makes you a man and helps with drive, healthy bones and Muscle development and there are negative consequences to lowering it.
I am 67 and healthier than I have been in a long time I would rather live another ten years healthy and active then 15 in the nursing home.
There are a number of good YouTube videos from Urology seminars that address that address TRT after Prostate cancer.

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@narus Een testosteron gehalte van 530 is toch een normale waarde, omgezet naar Nederlandse waarde is dit bij ons 19 ml/mol en dan wordt het als normale waarde gezien. heb je toch geen extra testosteron nodig.

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narus | @narus | Sep 4 11:22am

Testosterone therapy is no so simple as just looking at a number. You need to look at free testosterone, total testosterone, estradoil, Sex Horm Binding Glob, luteinizing hormone. Treatment decisions should be based on symptoms, not just numbers. I take a pretty low dose 10mg/week IM. I have stopped taking it in the past and my issues returned no sex drive, loss of muscle strength in my legs and fatigue.
The negative issue of testosterone therapy is higher hemoglobin and I keep that in check by donating blood.
Maybe I will not live to be 100 but my quality of life is much better.

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