Does anyone have first hand experience with Nanoknife procedure?

Posted by halton83 @halton83, Jun 28 7:50pm

Has anyone experienced Nano Knife prostate ablation postop experience over variuos time periods. PSA 3 months after, after affects and thoghts on longer term

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Profile picture for cole5055 @cole5055

I am with you! 20yr Air Force veteran
Desert Storm. When my PSA climbed to 5.1 ... 11-7-2023 the VA immediately wanted to do a trans-rectal Biopsy and remove my prostrate I said let me do some research. I felt very uncomfortable even talking with the VA Doctor! I fought with the VA to see a Urologist out side the VA for two years meanwhile my PSA continued its climb!
Finally got approved to see a Urologist and did the trans-rectal random Biopsy, I asked the Doctor what are the chances of finding anything he said 50/50 I regret doing it He also wanted to remove my prostrate After another year of MRI's & Pet-ct scans you could clearly see my Pirads 5 targets which the random Biopsy missed!
Once I turned 65 it seems the sky opened up ..... I had Medicare A&B and Tricare for life which meant I could chose everything!
The Doctor, hospital and the exact treatment I wanted "NOT WHAT THE DOCTORS SCARE YOU INTO" This year Mar 12-2026 1 got the Trans-perineal Targeted fusion Biopsy and finally found Gleason 3+4=7 one main target and one smaller target. May 19-2026 I chose Nano Knife at Mayo Clinic AZ it seemed to be the best option for my particular situation at the time of treatment my PSA climbed to 20.1.
Just had a recent PSA test it came back 2.9 and still dropping I have a follow up
August 21-2026 with Mayo hoping for another big drop. Hope this info helps you 😊

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@cole5055 I go to the Mayo in Phoenix also. Is Dr. Frendl your urologist? He is mine and I think he does NanoKnife. I am still on A/S, but some day may need treatment. Thanks. I will say a prayer your PSA went well.

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Hi Bob,

Yes, Dr. Frendl is my Doctor / Urologist at Mayo and did my Nano Knife procedure. The procedure took just over two hours. Recovery is not pleasant with a catheter for 10 days. And had to go to the emergency room for a second catheter after the first one was removed. About 6 weeks to get back to semi normal……… May 19-2026 as of August 21-2026 my PSA 2.2 . And yes, by all means have a back-up plan 🙂 Thank you for your prayers 🙂

No side effects other than the recovery itself 🙂

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Profile picture for cole5055 @cole5055

Hi Bob,

Yes, Dr. Frendl is my Doctor / Urologist at Mayo and did my Nano Knife procedure. The procedure took just over two hours. Recovery is not pleasant with a catheter for 10 days. And had to go to the emergency room for a second catheter after the first one was removed. About 6 weeks to get back to semi normal……… May 19-2026 as of August 21-2026 my PSA 2.2 . And yes, by all means have a back-up plan 🙂 Thank you for your prayers 🙂

No side effects other than the recovery itself 🙂

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@cole5055 I had Nanoknife surgery on August 21. Dr Strauss at University Colorado Anschutz Hospital was my dr. I had a tumor 1 mm in size. The dr said the treatment was successful. It took around 1 hour. He is a fantastic dr. Had to wear a catheter for 1 week. It was removed on Friday. What a relief. My energy level continues to get better. I walked 6,000 steps today
.

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