How often do you think a bone marrow biopsy is required?

I have had one only @ diagnosis. I have smoldering multiple myeloma. Since my bloodwork is stable my Doctor won't preform another one until I would have to start treatment.

Interesting conversation. I had no idea what a BMB was until my very low blood numbers, and my new hematologist wanted a closer view of the blood cell engine in my body. Until July of 2021 and a diagnosis of breast cancer, I seldom was ever sick. I was not really bothered by the BMB test and do like the idea that a blood test is being developed that can provide the same results. Having MDS and a few genetic mutations, I had i believe 4 if not 5 as i had a bone marrow transplant. Crazy how i do not remember. Living in today!!

@cetzler I’m 73. To clarify, the dosage I mentioned above is weekly. I just take them in the morning after getting up so pre-breakfast (if I have any) and I’ve had no side effects. I was originally told to avoid aspirin but, if necessary, take ibuprofen but I’ve never had a need for it. I was given the option to start HU but, as best I remember, within a year of diagnosis I started and the dosage was tweaked until platelets came down within normal range. Keep in mind, when I was first diagnosed, my platelets were at 1.3 M. For many years I was on 500 mg daily. Recently my dosage was adjusted a bit, adding an additional 500 mg three days per week (T, Th, S). On those days, I just take the 2 capsules together in the morning with no issues. HU has had no negative impact on me but others have mentioned various issues here. I wish you well 💕

@hsminc
Same. I don’t agree to anything invasive unless I can be given compelling reason.