Evenity after bad side effects from both Tymlos and Prolia

Posted by jencc7 @jencc7, 23 hours ago

I’ve had bad side effects from every osteo medication I’ve tried. The last was Tymlos and I had terrible back pain and spasms minutes after taking my first injection. Now they want me to try Evenity! Anyone had a similar experience?

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gigilapoisson | @gigilapoisson | 5 hours ago

I was on Tymlos and had difficulty with it as well. It gave me severe nausea and vomiting after several days of the 1st injection. I am now on Evenity infusions. I experience exhaustion with each infusion, and sleep for 18 hours afterwards. I just plan for it now and am able to deal with it.

joanneshap | @joanneshap | 3 hours ago

Had one Evenity shot. Just sore arms. Will watch for exhaustion as didn’t realize that could be a side affect

beanieone | @beanieone | 2 hours ago

@jencc7

I began my journey with Reclast infusions c. 2011 and, including the last one in June, have had no adverse reactions.

I started Tymlos in late 2022; it had pretty debilitating side effects. I refused to take it after 9-1/2 months of PT, pain management, Zofran, ibuprofen, acetaminophen, more ibuprofen, more acetaminophen . . . trying to convince my doc that the med was the culprit in my agony - he said my reactions weren't listed on the Tymlos website. I felt, at different times, he thought my various maladies were mental, not physical. Anyway . . .

In July, 2023, I took my first Evenity shots and never looked back. No issues except for that pesky "shot arm" pain for a couple of days. My DEXA in 2025 showed great gains. As a note: I used Tymlos for 9-1/2 months and Evenity for a full twelve months, so I can't be 100% sure which of these meds worked better for me.

Sorry to hear of your issues. All the best to you! Cheers!