Has anyone ever tried Lyrica for neuropathy?

@ericmm I’m also taking ALA in combination with Lyrica but has only been a short time so I don’t have any conclusions yet.

@blowerk1216
I’m on R-ALA. It’s the purest form. If the bottle says just ALA It’s actually S-ALA and the S stands for synthetic. It’s not ad good. IMO

@llanfi
I would ask the Doctor to lower the dose of Pregabalin at night since there are severe risks of combining Tramadol and pregabalin.
Maybe don't take both?
My experience :
I had Shingles at age 76 last year and Pregabalin greatly relieved my Nerve pain . 300 was way too much that I stumbled to walk more than a few steps. Finally 100mg was acceptable for the pain relief but I could barely talk clearly on 100.
After 6 weeks the blisters from shingles cleared up but the burning and itchiness remains on my jaw and cheek.
I now only take 50mg/day as needed.
Please see another MD if possible about combination of Tramadol & Pregabalin.
Pregabalin (alone) at a Lower Dose might be all you need for Neuropathy (nerve pain).
I'm worried for you!

@sanditx
I was on the lowest dose of Lyrica and the fatigue was so bad I could hardly walk to my car. So, I threw them out and went to a nature store and bought 600 mg of Alpha Lipoic Acid which the owner takes and sells like hotcakes - had only one bottle left. I got the brand Source Naturals also with a good vitamin B complex as the B12 is needed with this pins and needle condition and was told your body pees out the excess B it doesn't need. I am 90% better thanks to these two supplements. Good Luck

Have had PN for at least 20 years- not diabetic but lower back injury in my younger days considered to be my problem (now 85)
Take pregagalin (Lyrica)100mg after evening meal prior to bed time /no medication during the day and yes some days if I dont rest occasionally it can be somewhat painful - most nights this is enough Lyrica to allow a reasonable night’s sleep. I am Australian and appreciate Mayo Clinic to allow me to be involved. — John G

I have been taking pregalbin 150 mg per day, as prescribed by an expert neurologist some years ago. This was after extensive tests at a neurology lab. The neurologist told me that she knew of no cure for my neurapathy. It has been getting steadily worse, but the discomfort is reduced with 100 mg tramadol per day.
I have recently started with magnesium glycinate and it seems to help.
Taking the pregalbin at bedtime gives me a good night's sleep, but I wake up quite disoriented. My GP says that this is acceptable, and I find that I am only fitfully asleep without the pregalbin.
I am 85 years old and have cervical stenosis as well as arthritis in my back, so the tramadol is supplemented with Celebrex.
I find that gentle foot massage and pedicure helps a bit, but I warn against vigourous foot massage because it seems to inflame the neurapathy for a couple of days afterwards. I also have an electical foot massager that I bought for about $100 from Amazon, It has a heater that gives me some relaxation, but doesn't reduce the numbness in my calves and feet.

@llanfi
Thanks Mary for all of the additional information you provided on your health history.
I have had neuropathy for approximately 7 years it has mostly remained in my numb feet. I also have severe Osteoarthritis. Over the years , I was uncertain as to what caused my pain. A long story of search entailed, much too long for this message. I will soon arrive at my 79th birthday and was extremely active in Playing pickleball until June of this year. I honestly have found most doctors to be of no help, when it comes to the above issues. Perhaps a Neurologist may be helpful if the neuropathy progresses. What seems to help me the most , is to insure that I keep moving at least 2,500 steps a day. I have restarted using Gabepetin 300 mg. 2 of 3 times per day. I felt that my first try, not enough time was spent 30 days to accurately judge its effectiveness. This time I intend to try at least 60 days.
If you have severe pain, you may
want to discuss with a pain management facility in your area
SCS Spinal Cord Stimulus ((Implant) it’s available as a five day external trial to determine its effectiveness. We each gave our own long pain history, so it’s hard to condense it into a small summary. Also, I am currently involved with a health care advocate , who stays in regular contact with me from an organization called ( Solace)
This advocate helps me through the maze of health care to find or discuss solutions. If you don’t have an advocate, This may be a very helpful avenue for you to connect with. I believe it is a no charge service.
If you have any questions, please feel free to communicate with me.
God bless in your pursuit of pain relief. Best Regards,
Gene

@llanfi I am starting lyrica Monday have been on gabapentin no luck. Used mirage for restless leg for over thirty years, have to ween off before going to lyrica. Hopefully it will help both a little. Have had three back surgeries to no avail and the stimulator in the spine to no good results. 84 and get 2 to four hours sleep at night, not good

@darla1958 Am trying to get onto low dose Naltrexone and hope the doctor will get me off Lyrica. In LDN support group which I am trying to gain as much insight into the drug as I can. Good for you being on LDN as it is a wonder drug and has little side effects.

Yes! My Nurse Practitioner gave me a prescription for 150mg of it. I took 2 pills at night before bed. It worked! Then after the prescription ran out, my Primary Doctor tried to lower my dosage to the 75mg pills. They were useless! He would not renew the 150s! Thanks a lot. Eventually, the NP renewed the inital prescrip of 150s. She had no problem with renewing it. Go figure.