@sanlee7 I've bn taking HU for 3 years, one tablet a day 5 days a week. Not bringing down platelets. I sleep a lot during the day. No energy. Have sharp pains in my head. I drink a lot of water because my mouth is dry also.

@sanlee7
Yes, to the dry mouth, and tiredness. I also have anemia because the Hydrea does affect and lower your red and white cells. Also itchy skin. I also had pretty bad heart burn right away but my hematologist that first diagnosed me put me on an acid reducer twice a day and now I am on one that I only have to take once a day. But as I have said, I have been on Hydrea for 11 years and 4 months now and it has been very effective in keeping my platelets down to a manageble count but seldom under 450,000. I have had minimal side effects and no more blood clots after the first one found at the time of diagnosis, for which I had to be on Warfarin for over a year. I am grateful for that. Oh, I am 76 years old so I was diagnosed at the age of 65.